YII3_SCHPO
ID YII3_SCHPO Reviewed; 625 AA.
AC Q9UTN0;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Uncharacterized transcriptional regulatory protein C139.03;
GN ORFNames=SPAC139.03;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227,
CC ECO:0000269|PubMed:16823372}. Cytoplasm, cytoskeleton, spindle
CC {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329670; CAB59617.1; -; Genomic_DNA.
DR PIR; T37604; T37604.
DR RefSeq; NP_593170.1; NM_001018567.2.
DR AlphaFoldDB; Q9UTN0; -.
DR SMR; Q9UTN0; -.
DR BioGRID; 278443; 19.
DR STRING; 4896.SPAC139.03.1; -.
DR iPTMnet; Q9UTN0; -.
DR MaxQB; Q9UTN0; -.
DR PaxDb; Q9UTN0; -.
DR PRIDE; Q9UTN0; -.
DR EnsemblFungi; SPAC139.03.1; SPAC139.03.1:pep; SPAC139.03.
DR GeneID; 2541956; -.
DR KEGG; spo:SPAC139.03; -.
DR PomBase; SPAC139.03; -.
DR VEuPathDB; FungiDB:SPAC139.03; -.
DR eggNOG; ENOG502REJ9; Eukaryota.
DR HOGENOM; CLU_437523_0_0_1; -.
DR InParanoid; Q9UTN0; -.
DR OMA; HSCLACR; -.
DR PhylomeDB; Q9UTN0; -.
DR PRO; PR:Q9UTN0; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0000785; C:chromatin; IDA:PomBase.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0072686; C:mitotic spindle; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IMP:PomBase.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; ISM:PomBase.
DR GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR GO; GO:1903931; P:positive regulation of pyrimidine-containing compound salvage; IMP:PomBase.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IMP:PomBase.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR CDD; cd00067; GAL4; 1.
DR Gene3D; 4.10.240.10; -; 1.
DR InterPro; IPR007219; Transcription_factor_dom_fun.
DR InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR Pfam; PF04082; Fungal_trans; 1.
DR Pfam; PF00172; Zn_clus; 1.
DR SMART; SM00906; Fungal_trans; 1.
DR SMART; SM00066; GAL4; 1.
DR SUPFAM; SSF57701; SSF57701; 1.
DR PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Cytoskeleton; DNA-binding; Metal-binding; Nucleus;
KW Reference proteome; Transcription; Transcription regulation; Zinc.
FT CHAIN 1..625
FT /note="Uncharacterized transcriptional regulatory protein
FT C139.03"
FT /id="PRO_0000310386"
FT DNA_BIND 23..51
FT /note="Zn(2)-C6 fungal-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT REGION 93..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 625 AA; 72131 MW; 6ED371EB64705799 CRC64;
MSETTKSGSK KSGQTSRRAI HSCLACRRKK LKCDHGRPCS NCLKRSTIQS CIYIDPGKTN
YDKRFERGSE ADELIDQLLS RVSMLEKRLN EVGTKSQSDY ENQQSHNLPS TPSADAETQR
NIGSLSVLDD TKSQYANYSS SSHVLWHLRN YHYLNLDQDI QEENDSLISP FFFRISPNES
AYDYLPPKKV SDILIEQFFF RCHMLINVLH RPTFYVRYND FWEKPHLRKP AFTSLLYAIY
ASALLATPVE VQKTWALGED ERYLQVDYHQ AFRYALASSN FLFEPDLNAL QALVLCQVVF
DSDRIRAPPS LVGLILHVAL CMGLHRDGSL YGLNPVISEI RRRVWANIVL SDLRTSETIG
YPPQIVEGNY DTRLPSALPD EIHNVDSSVI ISEATFVNII TKVSRAYSKC LKVLLGIIAP
NYTRLLELDR ELSNFFKELI EVNIPTSNTM HERHIRLLVS YLSNRFPILL HFPFLLKKNS
AQFAYSHSRA LESATLALNQ LYELGSNPEY SKYSWYLWRY PPFHPCIVLL LDLLNSQKII
YLDDERVVLL NKIFSLFPRS SGKEHYQKAW ALLQTSRAKV WEKLGLSTVD VSTTDVRLTN
FEFFDANNLD INWDDWDAIF QHCPF