YII9_YEAST
ID YII9_YEAST Reviewed; 205 AA.
AC P40500; D6VVJ8;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Uncharacterized membrane protein YIL089W;
GN OrderedLocusNames=YIL089W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169870;
RA Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D.,
RA Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E.,
RA Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C.,
RA Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V.,
RA Walsh S.V., Whitehead S., Barrell B.G.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome IX.";
RL Nature 387:84-87(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 208353 / W303-1A;
RX PubMed=16847258; DOI=10.1073/pnas.0604075103;
RA Kim H., Melen K., Oesterberg M., von Heijne G.;
RT "A global topology map of the Saccharomyces cerevisiae membrane proteome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006).
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
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DR EMBL; Z46728; CAA86705.1; -; Genomic_DNA.
DR EMBL; BK006942; DAA08464.1; -; Genomic_DNA.
DR PIR; S49791; S49791.
DR RefSeq; NP_012177.1; NM_001179437.1.
DR AlphaFoldDB; P40500; -.
DR SMR; P40500; -.
DR BioGRID; 34903; 45.
DR IntAct; P40500; 1.
DR STRING; 4932.YIL089W; -.
DR PaxDb; P40500; -.
DR EnsemblFungi; YIL089W_mRNA; YIL089W; YIL089W.
DR GeneID; 854719; -.
DR KEGG; sce:YIL089W; -.
DR SGD; S000001351; YIL089W.
DR VEuPathDB; FungiDB:YIL089W; -.
DR GeneTree; ENSGT00940000180819; -.
DR HOGENOM; CLU_113423_0_0_1; -.
DR OMA; FIFATHQ; -.
DR BioCyc; YEAST:G3O-31349-MON; -.
DR PRO; PR:P40500; -.
DR Proteomes; UP000002311; Chromosome IX.
DR RNAct; P40500; protein.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:SGD.
DR GO; GO:0000324; C:fungal-type vacuole; HDA:SGD.
DR GO; GO:0000328; C:fungal-type vacuole lumen; IDA:SGD.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005777; C:peroxisome; HDA:SGD.
DR InterPro; IPR031427; DUF4668.
DR Pfam; PF15701; DUF4668; 1.
PE 1: Evidence at protein level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..205
FT /note="Uncharacterized membrane protein YIL089W"
FT /id="PRO_0000202976"
FT TOPO_DOM 1..63
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 85..124
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 125..145
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 146..205
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 205 AA; 23859 MW; DFD2BC3E729367F5 CRC64;
MQRTRELESS VAIDQTEVPR SRFFIMVKKL SRVADIVYIV DTFLIPPLHP LKKQHPKVAK
FLKVQLVFDL ISLFIFATHQ LLLLEDGNFG KHYFKRKTKR CSKFSCSRCN ANAHHPKWFK
FKHSLLCLGT FCFGVYSLVK INKFFKTDQT VDLNRLLELF FWQLNAILNM KLFAFYGDHL
ESHSAPLDVY EDSFANKSSS GGDEV
