YIKC_SCHPO
ID YIKC_SCHPO Reviewed; 317 AA.
AC Q8TFH2;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 25-MAY-2022, entry version 114.
DE RecName: Full=Uncharacterized mitochondrial carrier PB17E12.12c;
GN ORFNames=SPAPB17E12.12c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000305}.
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DR EMBL; CU329670; CAD27505.1; -; Genomic_DNA.
DR RefSeq; NP_001018227.1; NM_001018707.2.
DR AlphaFoldDB; Q8TFH2; -.
DR SMR; Q8TFH2; -.
DR STRING; 4896.SPAPB17E12.12c.1; -.
DR MaxQB; Q8TFH2; -.
DR PaxDb; Q8TFH2; -.
DR EnsemblFungi; SPAPB17E12.12c.1; SPAPB17E12.12c.1:pep; SPAPB17E12.12c.
DR GeneID; 3361393; -.
DR KEGG; spo:SPAPB17E12.12c; -.
DR PomBase; SPAPB17E12.12c; -.
DR VEuPathDB; FungiDB:SPAPB17E12.12c; -.
DR eggNOG; KOG0752; Eukaryota.
DR HOGENOM; CLU_015166_10_9_1; -.
DR InParanoid; Q8TFH2; -.
DR OMA; KLPGMWA; -.
DR PhylomeDB; Q8TFH2; -.
DR PRO; PR:Q8TFH2; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; ISS:PomBase.
DR GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR GO; GO:0046964; F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity; ISO:PomBase.
DR GO; GO:1902557; F:5'-adenylyl sulfate transmembrane transporter activity; ISO:PomBase.
DR GO; GO:1990554; P:mitochondrial 3'-phospho-5'-adenylyl sulfate transmembrane transport; ISO:PomBase.
DR GO; GO:1990553; P:mitochondrial 5'-adenylyl sulfate transmembrane transport; ISO:PomBase.
DR GO; GO:0006839; P:mitochondrial transport; NAS:PomBase.
DR Gene3D; 1.50.40.10; -; 1.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; SSF103506; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Repeat; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..317
FT /note="Uncharacterized mitochondrial carrier PB17E12.12c"
FT /id="PRO_0000310799"
FT TRANSMEM 14..34
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 72..92
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 119..139
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 230..250
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 291..307
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT REPEAT 18..103
FT /note="Solcar 1"
FT REPEAT 113..217
FT /note="Solcar 2"
FT REPEAT 224..313
FT /note="Solcar 3"
SQ SEQUENCE 317 AA; 35466 MW; 4589A0E694820CF9 CRC64;
MQKDKFGPCA PSRIPLLSND LISMLSGGVA ATVSRTAVSP LERMKIIFQV QNNKEYTSLT
STLVKIWNRE GLIGFFRGNG TNCLRAFPYG AVQFATFNML KQRALKNRSH QNLENHERLL
FGAIAGAASC ATTYPLDIAR TRLSIETAGL TSRSLAINNV ANNSLKVKPL TLWSTLLYIV
QHEGGYPALY NGLPATLLNV VPYVSICFFT FEFCKQKFFS NADLTAFQKL FLGGFTGIIG
QTLTFPADVL RRRFQVNRIP GIGHNYKNIK SAIFHIYKTE GINGFFRGYS SNMLKIIPVM
SITWYTYETV SKMLHDL