ID   YIP12_SCHPO             Reviewed;         235 AA.
AC   P0CU09; Q9P347;
DT   07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT   07-SEP-2016, sequence version 1.
DT   25-MAY-2022, entry version 16.
DE   RecName: Full=Survival of motor neuron protein-interacting protein yip12;
DE            Short=SMN-interacting protein yip12;
DE   AltName: Full=Yab8-interacting protein 1-b;
GN   Name=yip12; Synonyms=yip1, ypi1-b; ORFNames=SPAPB17E12.02;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   INTERACTION WITH SMN1, AND SUBCELLULAR LOCATION.
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=10749973; DOI=10.1093/hmg/9.5.663;
RA   Hannus S., Buehler D., Romano M., Seraphin B., Fischer U.;
RT   "The Schizosaccharomyces pombe protein Yab8p and a novel factor, Yip1p,
RT   share structural and functional similarity with the spinal muscular
RT   atrophy-associated proteins SMN and SIP1.";
RL   Hum. Mol. Genet. 9:663-674(2000).
RN   [3]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-117 AND SER-118, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- SUBUNIT: Interacts with smn1. {ECO:0000269|PubMed:10749973}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:10749973}.
CC   -!- SIMILARITY: Belongs to the gemin-2 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAD27495.1; -; Genomic_DNA.
DR   RefSeq; NP_001018218.1; NM_001018698.2.
DR   RefSeq; NP_594775.1; NM_001020202.2.
DR   AlphaFoldDB; P0CU09; -.
DR   SMR; P0CU09; -.
DR   iPTMnet; P0CU09; -.
DR   EnsemblFungi; SPAC19B12.12c.1; SPAC19B12.12c.1:pep; SPAC19B12.12c.
DR   EnsemblFungi; SPAPB17E12.02.1; SPAPB17E12.02.1:pep; SPAPB17E12.02.
DR   GeneID; 2542486; -.
DR   GeneID; 3361408; -.
DR   KEGG; spo:SPAC19B12.12c; -.
DR   KEGG; spo:SPAPB17E12.02; -.
DR   PomBase; SPAPB17E12.02; yip12.
DR   VEuPathDB; FungiDB:SPAC19B12.12c; -.
DR   VEuPathDB; FungiDB:SPAPB17E12.02; -.
DR   OMA; DIFENCA; -.
DR   PRO; PR:P0CU09; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0032797; C:SMN complex; IBA:GO_Central.
DR   GO; GO:0000387; P:spliceosomal snRNP assembly; IBA:GO_Central.
DR   InterPro; IPR035426; Gemin2/Brr1.
DR   Pfam; PF04938; SIP1; 1.
PE   1: Evidence at protein level;
KW   Nucleus; Phosphoprotein; Reference proteome.
FT   CHAIN           1..235
FT                   /note="Survival of motor neuron protein-interacting protein
FT                   yip12"
FT                   /id="PRO_0000437231"
FT   REGION          1..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         117
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   MOD_RES         118
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
SQ   SEQUENCE   235 AA;  26994 MW;  2EC8D23A80FEAA8C CRC64;
     MPSKRKRNPL QYQTSGSLDE ETNQRSAFPQ IDNNSASESL EYDIPLDGLD YLATVREEAR
     KLVPFVAARR EPETRETIPL RKLEIEAGKK SFDPFLRYLL NIIDKEGERL EQYMESSSLD
     ASILPKNLQQ WRVYIEHKAP CWAILAVVDL ATVLEILESL SSWLEKDAID LQSQWIFCFC
     YKLPELLNGE DISTLRSVLK SLRSTHTSFP ALQMSASALQ AVLVYRYGQK DLFQT