ID   YIP6_SCHPO              Reviewed;         381 AA.
AC   Q9UT84;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Phospholipid scramblase family protein C343.06c;
GN   ORFNames=SPAC343.06c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1] {ECO:0000312|EMBL:CAB52269.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2] {ECO:0000305}
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the phospholipid scramblase family.
CC       {ECO:0000255}.
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DR   EMBL; CU329670; CAB52269.1; -; Genomic_DNA.
DR   PIR; T38655; T38655.
DR   RefSeq; NP_593426.1; NM_001018859.2.
DR   AlphaFoldDB; Q9UT84; -.
DR   BioGRID; 279583; 9.
DR   STRING; 4896.SPAC343.06c.1; -.
DR   MaxQB; Q9UT84; -.
DR   PaxDb; Q9UT84; -.
DR   PRIDE; Q9UT84; -.
DR   EnsemblFungi; SPAC343.06c.1; SPAC343.06c.1:pep; SPAC343.06c.
DR   GeneID; 2543151; -.
DR   KEGG; spo:SPAC343.06c; -.
DR   PomBase; SPAC343.06c; -.
DR   VEuPathDB; FungiDB:SPAC343.06c; -.
DR   eggNOG; KOG0621; Eukaryota.
DR   HOGENOM; CLU_023808_0_2_1; -.
DR   InParanoid; Q9UT84; -.
DR   OMA; FHTHRAF; -.
DR   PhylomeDB; Q9UT84; -.
DR   PRO; PR:Q9UT84; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0017128; F:phospholipid scramblase activity; ISM:PomBase.
DR   GO; GO:0017121; P:plasma membrane phospholipid scrambling; ISM:PomBase.
DR   InterPro; IPR005552; Scramblase.
DR   InterPro; IPR025659; Tubby-like_C.
DR   PANTHER; PTHR23248; PTHR23248; 1.
DR   Pfam; PF03803; Scramblase; 1.
DR   SUPFAM; SSF54518; SSF54518; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome.
FT   CHAIN           1..381
FT                   /note="Phospholipid scramblase family protein C343.06c"
FT                   /id="PRO_0000317215"
FT   REGION          336..369
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        339..363
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   381 AA;  43148 MW;  80FCB864ED025285 CRC64;
     MLEILWANIT PIQTFVSSNH LTMLYGLKRF GCRLYHHSKS TRYIDATAKV VSQEPAAISS
     TGAIPLNSPA APLLSQDVLI VERQLEMMNV FLGYEQANRY VILNQQGQHL GYIAEQGASS
     ILSSLSRQFF HTHRAFKADV MDSNGQLVLQ LNRPFSWINS RLQIHSIDYS KFSSTLVGEV
     LQKWHLWRRR YELFLAKRSM FEQFAKIDER VLSWEFLLRN EQDRILGSVS RNFMGLPREF
     FTDTGNYVLR FTSTSAANGS VNENQLLQAA HGIANDVCAR DMSLEERAVM LGSAVTIDFD
     YFSRIHGGPA LGLNIPFMFG GSSSNHDYPA EDLSAQEILK NDQETTPSTN DSSSETKSPF
     LSDADLDQQD FWDIFDRDGD D