ID   YIPF1_PONAB             Reviewed;         306 AA.
AC   Q5RBL0;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Protein YIPF1;
DE   AltName: Full=YIP1 family member 1;
GN   Name=YIPF1;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Interacts with YIPF6; this interaction may stabilize YIPF1.
CC       May also form a ternary complex with YIPF2 and YIPF6.
CC       {ECO:0000250|UniProtKB:Q9Y548}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network membrane
CC       {ECO:0000250|UniProtKB:Q9Y548}; Multi-pass membrane protein
CC       {ECO:0000250|UniProtKB:Q9Y548}. Golgi apparatus, trans-Golgi network
CC       membrane {ECO:0000250|UniProtKB:Q9Y548}. Late endosome membrane
CC       {ECO:0000250|UniProtKB:Q9Y548}. Note=Mainly localizes within
CC       medial-/trans-Golgi and trans-Golgi network (TGN), while less so within
CC       cis-Golgi. {ECO:0000250|UniProtKB:Q9Y548}.
CC   -!- SIMILARITY: Belongs to the YIP1 family. {ECO:0000305}.
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DR   EMBL; CR858630; CAH90850.1; -; mRNA.
DR   RefSeq; NP_001125485.1; NM_001132013.1.
DR   AlphaFoldDB; Q5RBL0; -.
DR   STRING; 9601.ENSPPYP00000001546; -.
DR   GeneID; 100172394; -.
DR   KEGG; pon:100172394; -.
DR   CTD; 54432; -.
DR   eggNOG; KOG3114; Eukaryota.
DR   InParanoid; Q5RBL0; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005797; C:Golgi medial cisterna; ISS:UniProtKB.
DR   GO; GO:0000138; C:Golgi trans cisterna; ISS:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR006977; Yip1_dom.
DR   InterPro; IPR039765; Yip5/YIPF1/YIPF2.
DR   PANTHER; PTHR12822; PTHR12822; 1.
DR   Pfam; PF04893; Yip1; 1.
PE   2: Evidence at transcript level;
KW   Endosome; Glycoprotein; Golgi apparatus; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..306
FT                   /note="Protein YIPF1"
FT                   /id="PRO_0000240870"
FT   TOPO_DOM        1..119
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q9Y548"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        141..162
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        163..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        184..200
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        222..227
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        228..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        249..256
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        257..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        278..306
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250|UniProtKB:Q9Y548"
FT   REGION          14..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..43
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        297
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   306 AA;  34259 MW;  135052D35EAE9FEC CRC64;
     MAAVDDLQFE EFGNAATSLT ANPDATTVNI EDPGETPKHQ SGSPRGSGRE EDDELLGNDD
     SDKTELLAGQ KKSSPFWTFE YYQTFFDVDT YQVFDRIKGS LLPIPGKNFV RLYIRSNPDL
     YGPFWICATL VFAIAISGNL SNFLIHLGEK TYRYVPEFRK VSIAATTIYA YAWLVPLALW
     GFLMWRNSKV MNIVSYSFLE IVCVYGYSLF IYIPTAILWI IPQKAVRWIL VMIALGISGS
     VLAMTFWPAV REDNRRVALA TIVTIVLLHM LLSVGCLAYF FDAPEMDHLP TTTATPNQTV
     AAAKSS