ID   CBIE_METJA              Reviewed;         211 AA.
AC   Q58917;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Probable cobalt-precorrin-7 C(5)-methyltransferase;
DE            EC=2.1.1.289;
DE   AltName: Full=Cobalt-precorrin-6Y C(5)-methyltransferase;
DE            Short=Cobalt-precorrin-6 methyltransferase;
DE            Short=Cobalt-precorrin-6Y methylase;
GN   Name=cbiE; Synonyms=cobL; OrderedLocusNames=MJ1522;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- FUNCTION: Catalyzes the methylation of C-5 in cobalt-precorrin-7 to
CC       form cobalt-precorrin-8. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Co-precorrin-7 + S-adenosyl-L-methionine = Co-precorrin-8X +
CC         H(+) + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:34591,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC         ChEBI:CHEBI:70791, ChEBI:CHEBI:70792; EC=2.1.1.289;
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis;
CC       cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route):
CC       step 8/10.
CC   -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC       {ECO:0000305}.
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DR   EMBL; L77117; AAB99541.1; -; Genomic_DNA.
DR   PIR; A64490; A64490.
DR   RefSeq; WP_010871046.1; NC_000909.1.
DR   AlphaFoldDB; Q58917; -.
DR   SMR; Q58917; -.
DR   STRING; 243232.MJ_1522; -.
DR   EnsemblBacteria; AAB99541; AAB99541; MJ_1522.
DR   GeneID; 1452430; -.
DR   KEGG; mja:MJ_1522; -.
DR   eggNOG; arCOG00650; Archaea.
DR   HOGENOM; CLU_089162_2_0_2; -.
DR   InParanoid; Q58917; -.
DR   OMA; DPCFSGL; -.
DR   OrthoDB; 90646at2157; -.
DR   PhylomeDB; Q58917; -.
DR   UniPathway; UPA00148; UER00229.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0043777; F:cobalt-precorrin-7 C15-methyltransferase activity; IEA:RHEA.
DR   GO; GO:0008276; F:protein methyltransferase activity; IEA:InterPro.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd11644; Precorrin-6Y-MT; 1.
DR   Gene3D; 3.30.950.10; -; 1.
DR   Gene3D; 3.40.1010.10; -; 1.
DR   InterPro; IPR000878; 4pyrrol_Mease.
DR   InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR   InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR   InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR   InterPro; IPR012818; CbiE.
DR   Pfam; PF00590; TP_methylase; 1.
DR   SUPFAM; SSF53790; SSF53790; 1.
DR   TIGRFAMs; TIGR02467; CbiE; 1.
PE   3: Inferred from homology;
KW   Cobalamin biosynthesis; Methyltransferase; Reference proteome;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..211
FT                   /note="Probable cobalt-precorrin-7 C(5)-methyltransferase"
FT                   /id="PRO_0000150410"
SQ   SEQUENCE   211 AA;  23806 MW;  279A1A2B14369510 CRC64;
     MIYIVGIGPG DREYLTLKAI KIVENADLVV GSKRALELFN IDEDKKITLT KNLIGELKEL
     IKNENIKNKK IAILSTGDPC FSGLLKTLLK IGAKKEDIEA ISGISSIQIA AAKLKISWED
     YYIITLHGKE ENRKKLLNLI KNHEKVIFLP NNLKEDAKFL INNGINPDTK IWVLENLTYE
     NEKISLKSLK EIANGDFSYL TVCVYEGDEE I