ID   YIPF2_RAT               Reviewed;         311 AA.
AC   Q5XIT3;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Protein YIPF2;
DE   AltName: Full=YIP1 family member 2;
GN   Name=Yipf2;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBUNIT: Interacts with YIPF6; this interaction may stabilize YIPF2.
CC       May also form a ternary complex with YIPF1 and YIPF6.
CC       {ECO:0000250|UniProtKB:Q9BWQ6}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network membrane
CC       {ECO:0000250|UniProtKB:Q9BWQ6}; Multi-pass membrane protein
CC       {ECO:0000250|UniProtKB:Q9BWQ6}. Golgi apparatus, trans-Golgi network
CC       membrane {ECO:0000250|UniProtKB:Q9BWQ6}. Late endosome membrane
CC       {ECO:0000250|UniProtKB:Q9BWQ6}. Note=Mainly localizes within
CC       medial-/trans-Golgi and trans-Golgi network (TGN), while less so within
CC       cis-Golgi. {ECO:0000250|UniProtKB:Q9BWQ6}.
CC   -!- SIMILARITY: Belongs to the YIP1 family. {ECO:0000305}.
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DR   EMBL; BC083587; AAH83587.1; -; mRNA.
DR   RefSeq; NP_001014230.1; NM_001014208.1.
DR   AlphaFoldDB; Q5XIT3; -.
DR   STRING; 10116.ENSRNOP00000012138; -.
DR   PaxDb; Q5XIT3; -.
DR   Ensembl; ENSRNOT00000012138; ENSRNOP00000012138; ENSRNOG00000022043.
DR   GeneID; 363027; -.
DR   KEGG; rno:363027; -.
DR   UCSC; RGD:1307512; rat.
DR   CTD; 78992; -.
DR   RGD; 1307512; Yipf2.
DR   eggNOG; KOG3114; Eukaryota.
DR   GeneTree; ENSGT00390000010157; -.
DR   HOGENOM; CLU_059606_1_1_1; -.
DR   InParanoid; Q5XIT3; -.
DR   OMA; AIGCKMY; -.
DR   OrthoDB; 1425332at2759; -.
DR   PhylomeDB; Q5XIT3; -.
DR   TreeFam; TF313536; -.
DR   PRO; PR:Q5XIT3; -.
DR   Proteomes; UP000002494; Chromosome 8.
DR   Bgee; ENSRNOG00000022043; Expressed in pancreas and 18 other tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0005797; C:Golgi medial cisterna; ISS:UniProtKB.
DR   GO; GO:0000138; C:Golgi trans cisterna; ISS:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR006977; Yip1_dom.
DR   InterPro; IPR039765; Yip5/YIPF1/YIPF2.
DR   PANTHER; PTHR12822; PTHR12822; 1.
DR   Pfam; PF04893; Yip1; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Endosome; Golgi apparatus; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BWQ6"
FT   CHAIN           2..311
FT                   /note="Protein YIPF2"
FT                   /id="PRO_0000241456"
FT   TOPO_DOM        2..120
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BWQ6"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        142..159
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        160..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        181..198
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        220..226
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        248..252
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        253..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        274..311
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BWQ6"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BWQ6"
SQ   SEQUENCE   311 AA;  34798 MW;  5510D28D44CB6286 CRC64;
     MAAADDLAFH EFEEAANLLA ETPDAATTSQ SDKLTSQEHV AVVVGSGIGY GAEGEEEDDK
     TSLLQDEKPQ PRFWTFDYYQ SFFDVDTSQV LDRIKGSLLP HPGHNFVRHH LRNRPDLYGP
     FWICATLAFV LAVTGNLTLV LAQRRDPSIH YSPQFHKVTI AGITIYCYAW LVPLALWGFL
     RWRQGTRERM GLYTFLETVC VYGYSLFVFI PTVVLWLIPV QWLQWLFGAL ALALSAAGLV
     FTLWPVVRED TRLVAAALLS IVVLLHALLA LGCKLYFFQP LPLDHVVPAP QAIPPSPNVL
     LPSSVQPMTT F