ID   YIPF3_XENLA             Reviewed;         341 AA.
AC   Q3B8G4; Q08B82;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Protein YIPF3;
DE   AltName: Full=YIP1 family member 3;
GN   Name=yipf3;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the maintenance of the Golgi structure. May play
CC       a role in hematopoiesis (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein. Golgi apparatus, cis-Golgi network membrane {ECO:0000250};
CC       Multi-pass membrane protein. Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the YIP1 family. {ECO:0000305}.
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DR   EMBL; BC106456; AAI06457.1; -; mRNA.
DR   EMBL; BC124836; AAI24837.1; -; mRNA.
DR   RefSeq; NP_001089118.1; NM_001095649.1.
DR   AlphaFoldDB; Q3B8G4; -.
DR   DNASU; 733391; -.
DR   GeneID; 733391; -.
DR   KEGG; xla:733391; -.
DR   CTD; 733391; -.
DR   Xenbase; XB-GENE-6253246; yipf3.L.
DR   OMA; YHKIVED; -.
DR   OrthoDB; 1332379at2759; -.
DR   Proteomes; UP000186698; Chromosome 5L.
DR   Bgee; 733391; Expressed in internal ear and 19 other tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   InterPro; IPR026637; YIPF3.
DR   PANTHER; PTHR15627:SF14; PTHR15627:SF14; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Cytoplasm; Differentiation; Glycoprotein; Golgi apparatus;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..341
FT                   /note="Protein YIPF3"
FT                   /id="PRO_0000244451"
FT   TOPO_DOM        1..146
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q9GZM5"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        168..185
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        207..212
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        234..242
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        243..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        264..272
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        273..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        294..341
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250|UniProtKB:Q9GZM5"
FT   REGION          26..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        330
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   341 AA;  37624 MW;  53E9C678AEC9D645 CRC64;
     MANSSGSSRN LTAADWGGFD DNMQSGGGAA VIDMENMDDT SGSSFEDMGE IHQHMKEEEE
     EVEGEGVPED GEEDGAFLGM KGVQGQLGRQ VADEMWQAGK RQASKAFNLY ANIDILRPYF
     DVEPIQVRHR LLESMIPVKM ISFPQKIAGE LYGPLMLVFT MVAILLHGMK SSGTIIREGT
     LMGTAIGTCF GYWLGVSSFI YFLAYLCNAQ ITMLQTLSLL GYGLFGHCIV LFITYNIHFH
     SLFYIFWLCI GGLSTLRMVA VLLSRTVGHT QRLIVCGTMA ALHMLFLLYL HFAYHKVVEG
     ILDTLDGQNV PLPIQRVARD LPVGPNTVLN ATVQVLLAHS R