ID   YIPF4_DANRE             Reviewed;         237 AA.
AC   Q6NYF1;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Protein YIPF4;
DE   AltName: Full=YIP1 family member 4;
GN   Name=yipf4; ORFNames=zgc:77069;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the maintenance of the Golgi structure.
CC       {ECO:0000250|UniProtKB:Q9BSR8}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network membrane
CC       {ECO:0000250|UniProtKB:Q9BSR8}; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the YIP1 family. {ECO:0000305}.
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DR   EMBL; BC066619; AAH66619.1; -; mRNA.
DR   RefSeq; NP_998056.1; NM_212891.1.
DR   AlphaFoldDB; Q6NYF1; -.
DR   STRING; 7955.ENSDARP00000045098; -.
DR   PaxDb; Q6NYF1; -.
DR   Ensembl; ENSDART00000045099; ENSDARP00000045098; ENSDARG00000030957.
DR   Ensembl; ENSDART00000187383; ENSDARP00000150916; ENSDARG00000109994.
DR   GeneID; 405827; -.
DR   KEGG; dre:405827; -.
DR   CTD; 84272; -.
DR   ZFIN; ZDB-GENE-040426-2253; yipf4.
DR   eggNOG; KOG3103; Eukaryota.
DR   GeneTree; ENSGT00940000153168; -.
DR   HOGENOM; CLU_072083_0_0_1; -.
DR   InParanoid; Q6NYF1; -.
DR   OMA; TMWFCGG; -.
DR   OrthoDB; 1242956at2759; -.
DR   PhylomeDB; Q6NYF1; -.
DR   TreeFam; TF315055; -.
DR   PRO; PR:Q6NYF1; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 17.
DR   Bgee; ENSDARG00000030957; Expressed in swim bladder and 27 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IBA:GO_Central.
DR   InterPro; IPR045231; Yip1/4-like.
DR   InterPro; IPR006977; Yip1_dom.
DR   PANTHER; PTHR21236; PTHR21236; 1.
DR   Pfam; PF04893; Yip1; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..237
FT                   /note="Protein YIPF4"
FT                   /id="PRO_0000242636"
FT   TOPO_DOM        1..106
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q9BSR8"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        128..131
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        153..160
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        182..188
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        189..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        210..216
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        217..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   237 AA;  26630 MW;  F6ACE50100AFD01A CRC64;
     MQFSPTNGDF TFVSSTDAEE LSGTIDAPDI TLNMGPESNR DTYATTFLRQ RGYGWLLEVE
     EEESEDTKPL LEELDIDLKD IYYKIRCVLM PMPSLGFNRQ VVRDNPDFWG PLAVVLLFSM
     ISIYGQFRVV SWIITIWIFG SLTIFLLARV LGGEVSYGQV LGVIGYSLLP LIVIAPLLLV
     IGGFEVVSTL IKLFGVFWAA YSAASLLVGD EFKTKKPLLI YPIFLLYIYF LSLYTGV