YIPF4_RAT
ID YIPF4_RAT Reviewed; 246 AA.
AC Q5M7T4;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-2005, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Protein YIPF4;
DE AltName: Full=YIP1 family member 4;
GN Name=Yipf4;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: Involved in the maintenance of the Golgi structure.
CC {ECO:0000250|UniProtKB:Q9BSR8}.
CC -!- SUBUNIT: Interacts with YIPF3 and YIPF5.
CC {ECO:0000250|UniProtKB:Q9BSR8}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network membrane
CC {ECO:0000250|UniProtKB:Q9BSR8}; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the YIP1 family. {ECO:0000305}.
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DR EMBL; BC088468; AAH88468.1; -; mRNA.
DR RefSeq; NP_001009712.1; NM_001009712.1.
DR AlphaFoldDB; Q5M7T4; -.
DR BioGRID; 263649; 1.
DR STRING; 10116.ENSRNOP00000007607; -.
DR jPOST; Q5M7T4; -.
DR PaxDb; Q5M7T4; -.
DR PRIDE; Q5M7T4; -.
DR GeneID; 362699; -.
DR KEGG; rno:362699; -.
DR UCSC; RGD:1310157; rat.
DR CTD; 84272; -.
DR RGD; 1310157; Yipf4.
DR VEuPathDB; HostDB:ENSRNOG00000005610; -.
DR eggNOG; KOG3103; Eukaryota.
DR HOGENOM; CLU_072083_0_0_1; -.
DR InParanoid; Q5M7T4; -.
DR OMA; TMWFCGG; -.
DR OrthoDB; 1242956at2759; -.
DR PhylomeDB; Q5M7T4; -.
DR PRO; PR:Q5M7T4; -.
DR Proteomes; UP000002494; Chromosome 6.
DR Bgee; ENSRNOG00000005610; Expressed in stomach and 20 other tissues.
DR Genevisible; Q5M7T4; RN.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IBA:GO_Central.
DR InterPro; IPR045231; Yip1/4-like.
DR InterPro; IPR006977; Yip1_dom.
DR PANTHER; PTHR21236; PTHR21236; 1.
DR Pfam; PF04893; Yip1; 1.
PE 2: Evidence at transcript level;
KW Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..246
FT /note="Protein YIPF4"
FT /id="PRO_0000242634"
FT TOPO_DOM 1..115
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250|UniProtKB:Q9BSR8"
FT TRANSMEM 116..136
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 137..140
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 162..168
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 190..197
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 198..218
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 219..225
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 246 AA; 27283 MW; CE59292A71ED818F CRC64;
MQPPGPPPAY APANGDFTFV SSADAEDLSG SIAAPDVKLN LGVSGDFIKE STATTFLRQR
GYGWLLEVED EDPEDNKPLL EELDIDLKDI YYKIRCVLMP MPSLGFNRQV VRDNPDFWGP
LAVVLFFSMI SLYGQFRVVS WIITIWIFGS LTIFLLARVL GGEVAYGQVL GVIGYSLLPL
IVIAPILLVV GSFEMVSTLI KLFGVFWAAY SAASLLVGEE FKTKKPLLIY PIFLLYIYFL
SLYTGV
