ID   YIPF5_DANRE             Reviewed;         257 AA.
AC   Q6P5I8; Q6TNQ6; Q7ZWD2;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Protein YIPF5;
DE   AltName: Full=YIP1 family member 5;
GN   Name=yipf5; ORFNames=zgc:56513, zgc:77939;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney marrow;
RX   PubMed=15520368; DOI=10.1073/pnas.0407241101;
RA   Song H.-D., Sun X.-J., Deng M., Zhang G.-W., Zhou Y., Wu X.-Y., Sheng Y.,
RA   Chen Y., Ruan Z., Jiang C.-L., Fan H.-Y., Zon L.I., Kanki J.P., Liu T.X.,
RA   Look A.T., Chen Z.;
RT   "Hematopoietic gene expression profile in zebrafish kidney marrow.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:16240-16245(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=SJD;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in transport between endoplasmic reticulum and
CC       Golgi. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000250|UniProtKB:Q9EQQ2}; Multi-pass membrane protein. Golgi
CC       apparatus, cis-Golgi network membrane {ECO:0000250|UniProtKB:Q969M3};
CC       Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the YIP1 family. {ECO:0000305}.
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DR   EMBL; AY391461; AAQ91273.1; -; mRNA.
DR   EMBL; BC049469; AAH49469.1; -; mRNA.
DR   EMBL; BC062871; AAH62871.1; -; mRNA.
DR   RefSeq; NP_956589.1; NM_200295.1.
DR   AlphaFoldDB; Q6P5I8; -.
DR   STRING; 7955.ENSDARP00000009453; -.
DR   PaxDb; Q6P5I8; -.
DR   Ensembl; ENSDART00000008593; ENSDARP00000009453; ENSDARG00000007279.
DR   GeneID; 393265; -.
DR   KEGG; dre:393265; -.
DR   CTD; 81555; -.
DR   ZFIN; ZDB-GENE-040426-1057; yipf5.
DR   eggNOG; KOG3103; Eukaryota.
DR   GeneTree; ENSGT00940000153168; -.
DR   HOGENOM; CLU_074741_2_0_1; -.
DR   InParanoid; Q6P5I8; -.
DR   OMA; IGINFDH; -.
DR   OrthoDB; 1457080at2759; -.
DR   PhylomeDB; Q6P5I8; -.
DR   TreeFam; TF313100; -.
DR   PRO; PR:Q6P5I8; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 21.
DR   Bgee; ENSDARG00000007279; Expressed in blastula and 30 other tissues.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IBA:GO_Central.
DR   InterPro; IPR045231; Yip1/4-like.
DR   PANTHER; PTHR21236; PTHR21236; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane;
KW   Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..257
FT                   /note="Protein YIPF5"
FT                   /id="PRO_0000234333"
FT   TOPO_DOM        1..124
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q969M3"
FT   TRANSMEM        125..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        146
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        168..173
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        195..196
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        197..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        218..236
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        237..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        34
FT                   /note="P -> S (in Ref. 1; AAQ91273)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        47
FT                   /note="M -> V (in Ref. 2; AAH49469)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        110
FT                   /note="V -> A (in Ref. 2; AAH49469)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        165
FT                   /note="C -> S (in Ref. 2; AAH49469)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   257 AA;  27877 MW;  41A7F4EE651CF91A CRC64;
     MSGFDNFNTD FYQSSYSVDD QNQGGYGYSN TDEPYKPYGQ YDYSQPMGYS AAPGMMQPQQ
     PYTGQIYQPT PAFTPTSSQS MYSSSFEDEP PLLEELGINF DHIWQKTLTV LHPLKASDGS
     IMNETDLAGP MVFCLAFGAT LLLTGKIQFG YVYGISAIGC LGMYCLLNLM SMTGVSFGCV
     ASVLGYCLLP MIILSSFGVI FSLQGIMGII LTAAIIGWCS LSASKIFISA LAMDGQQLLV
     AYPCALLYGV FALISVF