ID   YIPF5_XENTR             Reviewed;         256 AA.
AC   Q66KA5;
DT   16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Protein YIPF5;
DE   AltName: Full=YIP1 family member 5;
GN   Name=yipf5;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in transport between endoplasmic reticulum and
CC       Golgi. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000250|UniProtKB:Q9EQQ2}; Multi-pass membrane protein. Golgi
CC       apparatus, cis-Golgi network membrane {ECO:0000250|UniProtKB:Q969M3};
CC       Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the YIP1 family. {ECO:0000305}.
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DR   EMBL; BC080486; AAH80486.1; -; mRNA.
DR   EMBL; BC089666; AAH89666.1; -; mRNA.
DR   RefSeq; NP_001007977.1; NM_001007976.2.
DR   RefSeq; XP_017947537.1; XM_018092048.1.
DR   AlphaFoldDB; Q66KA5; -.
DR   PaxDb; Q66KA5; -.
DR   DNASU; 493343; -.
DR   Ensembl; ENSXETT00000012028; ENSXETP00000012028; ENSXETG00000005469.
DR   GeneID; 493343; -.
DR   KEGG; xtr:493343; -.
DR   CTD; 81555; -.
DR   Xenbase; XB-GENE-977461; yipf5.
DR   eggNOG; KOG3103; Eukaryota.
DR   HOGENOM; CLU_074741_2_0_1; -.
DR   InParanoid; Q66KA5; -.
DR   OMA; IGINFDH; -.
DR   OrthoDB; 1457080at2759; -.
DR   PhylomeDB; Q66KA5; -.
DR   TreeFam; TF313100; -.
DR   Proteomes; UP000008143; Chromosome 3.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000005469; Expressed in egg cell and 14 other tissues.
DR   ExpressionAtlas; Q66KA5; differential.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IBA:GO_Central.
DR   InterPro; IPR045231; Yip1/4-like.
DR   PANTHER; PTHR21236; PTHR21236; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane;
KW   Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..256
FT                   /note="Protein YIPF5"
FT                   /id="PRO_0000234335"
FT   TOPO_DOM        1..125
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q969M3"
FT   TRANSMEM        126..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        147
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        169..172
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        194..195
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        196..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        217..235
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        236..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   256 AA;  27885 MW;  56B170CA535A03D5 CRC64;
     MSNFDNFNTD FYQTSYSIDD QSQGYNYNAG GAQHSKQYAY DPYSQQGGFI PPEMMNQQQP
     YTGQIYQPTQ TYTPAATDSV YGSTFDDEPP LLEELGINFD HIWQKTLTVL HPLKVADGNI
     MNETDLAGPM VFCLAFGATL LLAGKIQFGY VYGISAIGCL GMYCLLNLMS MTGVSFGCVS
     SVLGYCLLPM IILSSFAVIF SLQGILGIVL AALIIGWCSF SASKIFISAL AMDGQQVLVA
     YPCALLYGVF ALISVF