ID   YIPF6_BOVIN             Reviewed;         236 AA.
AC   A6QLC6;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Protein YIPF6;
DE   AltName: Full=YIP1 family member 6;
GN   Name=YIPF6;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal skin;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be required for stable YIPF1 and YIPF2 protein
CC       expression. {ECO:0000250|UniProtKB:Q96EC8}.
CC   -!- SUBUNIT: Predominantly interacts with YIPF1 or YIPF2, but may also form
CC       a ternary complex with YIPF1 and YIPF2. This interaction may stabilize
CC       YIPF1 and YIPF2. {ECO:0000250|UniProtKB:Q96EC8}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000250|UniProtKB:Q96EC8}; Multi-pass membrane protein
CC       {ECO:0000250|UniProtKB:Q96EC8}. Note=Evenly distributed between
CC       cis- and trans-Golgi apparatus. Mainly localizes within medial-/trans-
CC       Golgi and trans-Golgi network (TGN), while less so within cis-Golgi.
CC       {ECO:0000250|UniProtKB:Q96EC8}.
CC   -!- SIMILARITY: Belongs to the YIP1 family. {ECO:0000305}.
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DR   EMBL; BC147916; AAI47917.1; -; mRNA.
DR   RefSeq; NP_001094676.1; NM_001101206.1.
DR   AlphaFoldDB; A6QLC6; -.
DR   STRING; 9913.ENSBTAP00000002566; -.
DR   PaxDb; A6QLC6; -.
DR   PRIDE; A6QLC6; -.
DR   Ensembl; ENSBTAT00000002566; ENSBTAP00000002566; ENSBTAG00000001977.
DR   GeneID; 540347; -.
DR   KEGG; bta:540347; -.
DR   CTD; 286451; -.
DR   VEuPathDB; HostDB:ENSBTAG00000001977; -.
DR   VGNC; VGNC:37028; YIPF6.
DR   eggNOG; KOG2946; Eukaryota.
DR   GeneTree; ENSGT00940000153168; -.
DR   HOGENOM; CLU_059592_3_0_1; -.
DR   InParanoid; A6QLC6; -.
DR   OMA; CVMPLTV; -.
DR   OrthoDB; 1287193at2759; -.
DR   TreeFam; TF314563; -.
DR   Proteomes; UP000009136; Chromosome X.
DR   Bgee; ENSBTAG00000001977; Expressed in oviduct epithelium and 107 other tissues.
DR   ExpressionAtlas; A6QLC6; baseline.
DR   GO; GO:0005801; C:cis-Golgi network; IEA:Ensembl.
DR   GO; GO:0030134; C:COPII-coated ER to Golgi transport vesicle; IEA:Ensembl.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR   GO; GO:0005797; C:Golgi medial cisterna; ISS:UniProtKB.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000138; C:Golgi trans cisterna; ISS:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR   GO; GO:0060576; P:intestinal epithelial cell development; IEA:Ensembl.
DR   InterPro; IPR045231; Yip1/4-like.
DR   InterPro; IPR006977; Yip1_dom.
DR   PANTHER; PTHR21236; PTHR21236; 1.
DR   Pfam; PF04893; Yip1; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Golgi apparatus; Membrane; Phosphoprotein; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250|UniProtKB:Q96EC8"
FT   CHAIN           2..236
FT                   /note="Protein YIPF6"
FT                   /id="PRO_0000330340"
FT   TOPO_DOM        2..84
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q96EC8"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        106..115
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        137..146
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        168..184
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        206..212
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        234..236
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250|UniProtKB:Q96EC8"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96EC8"
FT   MOD_RES         7
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4QQU5"
SQ   SEQUENCE   236 AA;  26184 MW;  644ED5096FE99E54 CRC64;
     MAEAVESPGD PGTTTPRPLF AGLSDISISQ DIPVEGEITI PVRSRVREFD SSTLNESVQN
     TIMRDLKAVG KKFMHVLYPR KSNTLLRDWD LWGPLILCVT LALMLQRGSV DSEKDGGPQF
     AEVFVIVWFG AVTITLNSKL LGGNISFFQS LCVLGYCILP LTMAMLVCRL VLLAEPGPVN
     FMVRLFVVII MFAWSIVAST AFLADSQPPN RKALAVYPVF LFYFVISWMI LTFTPQ