ID   YIPF6_DANRE             Reviewed;         240 AA.
AC   Q6IQ85;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Protein YIPF6;
DE   AltName: Full=YIP1 family member 6;
GN   Name=yipf6; ORFNames=zgc:86904;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000250|UniProtKB:Q96EC8}; Multi-pass membrane protein
CC       {ECO:0000250|UniProtKB:Q96EC8}. Note=Evenly distributed between
CC       cis- and trans-Golgi apparatus. Mainly localizes within medial-/trans-
CC       Golgi and trans-Golgi network (TGN), while less so within cis-Golgi.
CC       {ECO:0000250|UniProtKB:Q96EC8}.
CC   -!- SIMILARITY: Belongs to the YIP1 family. {ECO:0000305}.
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DR   EMBL; BC071525; AAH71525.1; -; mRNA.
DR   RefSeq; NP_001002096.1; NM_001002096.1.
DR   AlphaFoldDB; Q6IQ85; -.
DR   STRING; 7955.ENSDARP00000071098; -.
DR   PaxDb; Q6IQ85; -.
DR   Ensembl; ENSDART00000076627; ENSDARP00000071098; ENSDARG00000054433.
DR   GeneID; 415186; -.
DR   KEGG; dre:415186; -.
DR   CTD; 286451; -.
DR   ZFIN; ZDB-GENE-040625-76; yipf6.
DR   eggNOG; KOG2946; Eukaryota.
DR   GeneTree; ENSGT00940000153168; -.
DR   InParanoid; Q6IQ85; -.
DR   OrthoDB; 1287193at2759; -.
DR   PhylomeDB; Q6IQ85; -.
DR   TreeFam; TF314563; -.
DR   Reactome; R-DRE-432722; Golgi Associated Vesicle Biogenesis.
DR   PRO; PR:Q6IQ85; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 5.
DR   Bgee; ENSDARG00000054433; Expressed in testis and 28 other tissues.
DR   ExpressionAtlas; Q6IQ85; baseline and differential.
DR   GO; GO:0005797; C:Golgi medial cisterna; ISS:UniProtKB.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000138; C:Golgi trans cisterna; ISS:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR045231; Yip1/4-like.
DR   InterPro; IPR006977; Yip1_dom.
DR   PANTHER; PTHR21236; PTHR21236; 1.
DR   Pfam; PF04893; Yip1; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..240
FT                   /note="Protein YIPF6"
FT                   /id="PRO_0000242671"
FT   TOPO_DOM        1..91
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:Q96EC8"
FT   TRANSMEM        92..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        113..125
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        126..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        147..149
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        171..172
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        194..215
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        216..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        237..240
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000250|UniProtKB:Q96EC8"
SQ   SEQUENCE   240 AA;  26320 MW;  F11DDC42BD7D1158 CRC64;
     MVVSHLNRTV TSLNELFEHH AHFAGLSDIS ISEDIPVEGD ISVPVGSQNA DNDFSTLDEP
     VKDTILRDLR AVGQKFVHVM YPKKSSALLR DWDLWGPLLL CVTLALMLQG GSADSEEDGR
     PQFAEVFVII WFGSVIITLN SKLLGGTISF FQSLCVLGYC ILPLTVAMIV CRIVLLGGSG
     VVSFAVRLIV VTASFSWSTF ASTAFLADSQ PTNRKALVVY PVFLFYFVIG WMILTFSPSH