YIPF6_DICDI
ID YIPF6_DICDI Reviewed; 182 AA.
AC Q54RZ2;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 18-MAR-2008, sequence version 2.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Protein YIPF6 homolog;
GN Name=yipf6; ORFNames=DDB_G0282825;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000250|UniProtKB:Q96EC8}; Multi-pass membrane protein
CC {ECO:0000250|UniProtKB:Q96EC8}. Note=Evenly distributed between
CC cis- and trans-Golgi apparatus. Mainly localizes within medial-/trans-
CC Golgi and trans-Golgi network (TGN), while less so within cis-Golgi.
CC {ECO:0000250|UniProtKB:Q96EC8}.
CC -!- SIMILARITY: Belongs to the YIP1 family. {ECO:0000305}.
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DR EMBL; AAFI02000047; EAL65992.2; -; Genomic_DNA.
DR RefSeq; XP_639345.2; XM_634253.3.
DR AlphaFoldDB; Q54RZ2; -.
DR STRING; 44689.DDB0233687; -.
DR PaxDb; Q54RZ2; -.
DR GeneID; 8623786; -.
DR KEGG; ddi:DDB_G0282825; -.
DR dictyBase; DDB_G0282825; yipf6.
DR eggNOG; KOG2946; Eukaryota.
DR HOGENOM; CLU_059592_3_0_1; -.
DR InParanoid; Q54RZ2; -.
DR OMA; CVMPLTV; -.
DR PhylomeDB; Q54RZ2; -.
DR PRO; PR:Q54RZ2; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0005797; C:Golgi medial cisterna; ISS:UniProtKB.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000138; C:Golgi trans cisterna; ISS:UniProtKB.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:InterPro.
DR InterPro; IPR045231; Yip1/4-like.
DR InterPro; IPR006977; Yip1_dom.
DR PANTHER; PTHR21236; PTHR21236; 1.
DR Pfam; PF04893; Yip1; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..182
FT /note="Protein YIPF6 homolog"
FT /id="PRO_0000330341"
FT TOPO_DOM 1..45
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250|UniProtKB:Q96EC8"
FT TRANSMEM 46..66
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 67..70
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 92..104
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 126..133
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 155..161
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 182 AA; 20417 MW; D0515F6569FCB974 CRC64;
MIESENPNTL DEPVIQTILR DLKMIGFKLY HVILPRGNAA NVLRDWDLWG PLILCLVMAI
FLSISAEEQK ALEFTIVFVV VWCGAAIVTV NGQLLCGNIS FFQSVCILGY CIFPLTIATI
IIWIIQNFTM IVKLPIVGGA WFWSSFASYG FLGSSVPESR RLLAVYPVLL FYLVIAWLVV
VQ