YIPF7_MOUSE
ID YIPF7_MOUSE Reviewed; 254 AA.
AC Q9JIM5;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Protein YIPF7;
DE AltName: Full=YIP1 family member 7;
GN Name=Yipf7; Synonyms=Yip1b;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX PubMed=11489904; DOI=10.1074/jbc.m106189200;
RA Tang B.L., Ong Y.S., Huang B., Wei S., Wong E.T., Qi R., Horstmann H.,
RA Hong W.;
RT "A membrane protein enriched in endoplasmic reticulum exit sites interacts
RT with COPII.";
RL J. Biol. Chem. 276:40008-40017(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Tongue;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Heart;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000269|PubMed:11489904}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:11489904}. Golgi apparatus, cis-Golgi network
CC membrane {ECO:0000250|UniProtKB:Q8N8F6}. Golgi apparatus, trans-Golgi
CC network membrane {ECO:0000250|UniProtKB:Q8N8F6}.
CC -!- TISSUE SPECIFICITY: Specifically expressed in the heart.
CC {ECO:0000269|PubMed:11489904}.
CC -!- SIMILARITY: Belongs to the YIP1 family. {ECO:0000305}.
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DR EMBL; AF217188; AAF78898.1; -; mRNA.
DR EMBL; AK009405; BAB26268.1; -; mRNA.
DR EMBL; BC089576; AAH89576.1; -; mRNA.
DR CCDS; CCDS19321.1; -.
DR RefSeq; NP_076273.1; NM_023784.5.
DR AlphaFoldDB; Q9JIM5; -.
DR STRING; 10090.ENSMUSP00000031045; -.
DR PhosphoSitePlus; Q9JIM5; -.
DR PaxDb; Q9JIM5; -.
DR PRIDE; Q9JIM5; -.
DR ProteomicsDB; 299630; -.
DR Antibodypedia; 23722; 31 antibodies from 14 providers.
DR Ensembl; ENSMUST00000031045; ENSMUSP00000031045; ENSMUSG00000029158.
DR GeneID; 75581; -.
DR KEGG; mmu:75581; -.
DR UCSC; uc008xqk.2; mouse.
DR CTD; 285525; -.
DR MGI; MGI:1922831; Yipf7.
DR VEuPathDB; HostDB:ENSMUSG00000029158; -.
DR eggNOG; KOG3103; Eukaryota.
DR GeneTree; ENSGT00940000153168; -.
DR HOGENOM; CLU_074741_2_0_1; -.
DR InParanoid; Q9JIM5; -.
DR OMA; VSCGCVA; -.
DR OrthoDB; 1457080at2759; -.
DR PhylomeDB; Q9JIM5; -.
DR TreeFam; TF313100; -.
DR BioGRID-ORCS; 75581; 1 hit in 73 CRISPR screens.
DR ChiTaRS; Yipf7; mouse.
DR PRO; PR:Q9JIM5; -.
DR Proteomes; UP000000589; Chromosome 5.
DR RNAct; Q9JIM5; protein.
DR Bgee; ENSMUSG00000029158; Expressed in interventricular septum and 80 other tissues.
DR ExpressionAtlas; Q9JIM5; baseline and differential.
DR Genevisible; Q9JIM5; MM.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0048280; P:vesicle fusion with Golgi apparatus; IBA:GO_Central.
DR InterPro; IPR045231; Yip1/4-like.
DR PANTHER; PTHR21236; PTHR21236; 1.
PE 2: Evidence at transcript level;
KW Endoplasmic reticulum; Golgi apparatus; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..254
FT /note="Protein YIPF7"
FT /id="PRO_0000333008"
FT TOPO_DOM 1..123
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250|UniProtKB:Q8N8F6"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 145
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 167..179
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 180..200
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 201..209
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 231..233
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 254 AA; 27490 MW; DF8E5793B5FEF240 CRC64;
MSNPEQYDMG FYQSNYIIDN QEPSCNDSNA YGNVYGYREP QATEQPSSPA PPEMFLPSDY
GGQLFQPASN LDYYSQSPSV DTFDEEPPLL EELGINFDHI WQKTLTVLNP MKPADGSIMN
ETDLTGPILF CVALGATLLM AGKAQFGYVY GMSAIGCLGI HALLNLMSNS GVSYGCVASV
LGYCLLPMVL LSSCAVFFSL QGTIGTMSAL LIITWCSLSA SKIFISALAM EGQQLLVAYP
CALLYGLFAL LTVF
