YIQ5_YEAST
ID YIQ5_YEAST Reviewed; 119 AA.
AC P40446; D6VVC2; Q05730;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 142.
DE RecName: Full=Putative nitrilase-like protein YIL165C;
GN OrderedLocusNames=YIL165C; ORFNames=YI9402.10AC;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Doignon F., Pilatte E., Aigle M.;
RT "Study of a DNA fragment involved in the ergosterol biosynthesis.";
RL Submitted (JUN-1992) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169870;
RA Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D.,
RA Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E.,
RA Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C.,
RA Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V.,
RA Walsh S.V., Whitehead S., Barrell B.G.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome IX.";
RL Nature 387:84-87(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
CC -!- SIMILARITY: Belongs to the carbon-nitrogen hydrolase superfamily.
CC Nitrilase family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. YIL165C seems to be the
CC C-terminal part of a putative nitrilase-like protein formed of
CC NIT1/YIL164C and YIL165C. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA46924.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; X66132; CAA46924.1; ALT_FRAME; mRNA.
DR EMBL; Z46921; CAA87027.1; -; Genomic_DNA.
DR EMBL; AY558540; AAS56866.1; -; Genomic_DNA.
DR EMBL; BK006942; DAA08388.1; -; Genomic_DNA.
DR PIR; S50362; S50362.
DR RefSeq; NP_012101.1; NM_001179513.1.
DR AlphaFoldDB; P40446; -.
DR SMR; P40446; -.
DR BioGRID; 34828; 48.
DR STRING; 4932.YIL165C; -.
DR PaxDb; P40446; -.
DR PRIDE; P40446; -.
DR EnsemblFungi; YIL165C_mRNA; YIL165C; YIL165C.
DR GeneID; 854641; -.
DR KEGG; sce:YIL165C; -.
DR SGD; S000001427; YIL165C.
DR VEuPathDB; FungiDB:YIL165C; -.
DR eggNOG; KOG0805; Eukaryota.
DR GeneTree; ENSGT00530000066464; -.
DR HOGENOM; CLU_116877_0_0_1; -.
DR InParanoid; P40446; -.
DR OMA; IACAKMD; -.
DR BioCyc; YEAST:G3O-31410-MON; -.
DR ChiTaRS; YIL165C; yeast.
DR Proteomes; UP000002311; Chromosome IX.
DR RNAct; P40446; protein.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0000422; P:autophagy of mitochondrion; IMP:SGD.
DR GO; GO:0016236; P:macroautophagy; IMP:SGD.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR Gene3D; 3.60.110.10; -; 1.
DR InterPro; IPR003010; C-N_Hydrolase.
DR InterPro; IPR036526; C-N_Hydrolase_sf.
DR InterPro; IPR044149; Nitrilases_CHs.
DR PANTHER; PTHR46044; PTHR46044; 1.
DR Pfam; PF00795; CN_hydrolase; 1.
DR SUPFAM; SSF56317; SSF56317; 1.
DR PROSITE; PS50263; CN_HYDROLASE; 1.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..119
FT /note="Putative nitrilase-like protein YIL165C"
FT /id="PRO_0000204050"
FT DOMAIN 1..82
FT /note="CN hydrolase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00054"
FT ACT_SITE 21
FT /note="Proton acceptor"
FT /evidence="ECO:0000250"
SQ SEQUENCE 119 AA; 12940 MW; 9667789C821E3559 CRC64;
MKNIAYEGRL FLISAVQFMP DATAMGFGEI IDQATGKRKL PGWPSADDNC INGGSVIIDP
YGEIIAGPLL GQEGLLTAEI NTDLIAEARF DLDPVGHYAR GDVFQLTVNE RSHDVKFTK
