YIQ6_YEAST
ID YIQ6_YEAST Reviewed; 542 AA.
AC P40445; D6VVC1;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 143.
DE RecName: Full=Uncharacterized transporter YIL166C;
GN OrderedLocusNames=YIL166C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169870;
RA Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D.,
RA Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E.,
RA Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C.,
RA Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V.,
RA Walsh S.V., Whitehead S., Barrell B.G.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome IX.";
RL Nature 387:84-87(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 208353 / W303-1A;
RX PubMed=16847258; DOI=10.1073/pnas.0604075103;
RA Kim H., Melen K., Oesterberg M., von Heijne G.;
RT "A global topology map of the Saccharomyces cerevisiae membrane proteome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006).
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Allantoate
CC permease family. {ECO:0000305}.
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DR EMBL; Z46921; CAA87026.1; -; Genomic_DNA.
DR EMBL; AY723832; AAU09749.1; -; Genomic_DNA.
DR EMBL; BK006942; DAA08387.1; -; Genomic_DNA.
DR PIR; S50361; S50361.
DR RefSeq; NP_012100.1; NM_001179514.1.
DR AlphaFoldDB; P40445; -.
DR SMR; P40445; -.
DR BioGRID; 34827; 34.
DR DIP; DIP-8099N; -.
DR STRING; 4932.YIL166C; -.
DR TCDB; 2.A.1.14.38; the major facilitator superfamily (mfs).
DR PaxDb; P40445; -.
DR PRIDE; P40445; -.
DR EnsemblFungi; YIL166C_mRNA; YIL166C; YIL166C.
DR GeneID; 854640; -.
DR KEGG; sce:YIL166C; -.
DR SGD; S000001428; YIL166C.
DR VEuPathDB; FungiDB:YIL166C; -.
DR eggNOG; KOG2533; Eukaryota.
DR HOGENOM; CLU_001265_2_0_1; -.
DR InParanoid; P40445; -.
DR OMA; SVICITQ; -.
DR BioCyc; YEAST:G3O-31411-MON; -.
DR PRO; PR:P40445; -.
DR Proteomes; UP000002311; Chromosome IX.
DR RNAct; P40445; protein.
DR GO; GO:0071944; C:cell periphery; HDA:SGD.
DR GO; GO:0000324; C:fungal-type vacuole; HDA:SGD.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031224; C:intrinsic component of membrane; IBA:GO_Central.
DR GO; GO:0015116; F:sulfate transmembrane transporter activity; IMP:SGD.
DR GO; GO:1901682; F:sulfur compound transmembrane transporter activity; IMP:SGD.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0008272; P:sulfate transport; IGI:SGD.
DR GO; GO:0000316; P:sulfite transport; IGI:SGD.
DR GO; GO:0072348; P:sulfur compound transport; IMP:SGD.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 1: Evidence at protein level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..542
FT /note="Uncharacterized transporter YIL166C"
FT /id="PRO_0000121373"
FT TOPO_DOM 1..78
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 100..119
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 120..140
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 141..147
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 169..176
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 198..208
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 209..229
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 230..241
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 263..326
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 327..347
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 348..359
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 360..380
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 381..387
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 388..408
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 409..416
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 417..437
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 438..482
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 483..503
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 504..542
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 542 AA; 61898 MW; F20F9A91333A9F6D CRC64;
MSVQKEEYDI VEKAQLSVSA ESLTSDSESI SHNPFDDFHK AERWRKVYES SGYEGLSKFD
PEFTWTKDEE KKLVRKMDLK IFLWVFIMFA FLDLIRKNIA RAVSDNFIVD LKMNTNDYNL
GQTVYLVIFL ASELPGNLLS KRFGPERVIP VQIVLWSVIC ITQAGLKNRG QFIATRCLLG
MVQGGFIPDN ILYLSYYYTG AELTFRLSFF WCAIPLFQIL GSLLASGIIE MRGIHNLAGW
QYLFIIEGFL SLSVGVASFY LMRRGPTQTG ESAFHKGKSL FTEYEEKIMV NRILRDDPSK
GDMSNRQPVT FKEILYTLTE FDLWPLFIQG ITAFISLQTV GSYLSLILKS LNYSTFLSNI
LAIPGQALLL INLPLAALLS RKLKEKSLCV GIANVWVLPF IVSLVALPTD TNPWIKYILL
TGILGLPYTH SILAGWVSEI SNSVRSRTVG TALYNMSAQV GAIIASNMYR NDDKPYYTRG
NKILLGFTCF NICMAVATKF YYISRNKYKD RKWNSMTKEE QINYLDTTKD KGMKRLDYRF
IH
