YITT_BACSU
ID YITT_BACSU Reviewed; 280 AA.
AC P39803; O08139; P70946;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 27-MAR-2002, sequence version 2.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=UPF0750 membrane protein YitT;
GN Name=yitT; Synonyms=yuxA; OrderedLocusNames=BSU11120;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / DB104;
RX PubMed=8226659; DOI=10.1128/jb.175.22.7130-7137.1993;
RA Shiga Y., Yamagata H., Udaka S.;
RT "Characterization of the gene encoding an intracellular proteinase
RT inhibitor of Bacillus subtilis and its role in regulation of the major
RT intracellular proteinase.";
RL J. Bacteriol. 175:7130-7137(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9025291; DOI=10.1099/00221287-143-1-175;
RA Levine A., Vannier F., Roche B., Autret S., Mavel D., Seror S.J.;
RT "A 10.3 kbp segment from nprB to argJ at the 102 degrees region of the
RT Bacillus subtilis chromosome.";
RL Microbiology 143:175-177(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9353931; DOI=10.1099/00221287-143-10-3305;
RA Medina N., Vannier F., Roche B., Autret S., Levine A., Seror S.J.;
RT "Sequencing of regions downstream of addA (98 degrees) and citG (289
RT degrees) in Bacillus subtilis.";
RL Microbiology 143:3305-3308(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the UPF0750 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; D16311; BAA03818.1; -; Genomic_DNA.
DR EMBL; Y09476; CAA70630.1; -; Genomic_DNA.
DR EMBL; Z79580; CAB01834.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB12952.1; -; Genomic_DNA.
DR PIR; A49921; A49921.
DR RefSeq; NP_388993.1; NC_000964.3.
DR RefSeq; WP_003245017.1; NZ_JNCM01000035.1.
DR AlphaFoldDB; P39803; -.
DR SMR; P39803; -.
DR STRING; 224308.BSU11120; -.
DR TCDB; 2.A.115.1.1; the novobiocin exporter (nbce) family.
DR PaxDb; P39803; -.
DR PRIDE; P39803; -.
DR EnsemblBacteria; CAB12952; CAB12952; BSU_11120.
DR GeneID; 939346; -.
DR KEGG; bsu:BSU11120; -.
DR PATRIC; fig|224308.179.peg.1194; -.
DR eggNOG; COG1284; Bacteria.
DR InParanoid; P39803; -.
DR OMA; IMIFNIP; -.
DR PhylomeDB; P39803; -.
DR BioCyc; BSUB:BSU11120-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.30.70.120; -; 1.
DR InterPro; IPR019264; DUF2179.
DR InterPro; IPR015867; N-reg_PII/ATP_PRibTrfase_C.
DR InterPro; IPR003740; YitT.
DR Pfam; PF10035; DUF2179; 1.
DR Pfam; PF02588; YitT_membrane; 1.
DR PIRSF; PIRSF006483; Membrane_protein_YitT; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..280
FT /note="UPF0750 membrane protein YitT"
FT /id="PRO_0000049590"
FT TRANSMEM 9..29
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 54..74
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 80..100
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 121
FT /note="V -> D (in Ref. 1; BAA03818)"
FT /evidence="ECO:0000305"
FT CONFLICT 226
FT /note="V -> L (in Ref. 1; BAA03818)"
FT /evidence="ECO:0000305"
FT CONFLICT 278
FT /note="R -> T (in Ref. 1; BAA03818)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 280 AA; 30535 MW; 4BF98B12B8DA59E7 CRC64;
MVLDQTKKLL IVIIGALLNA AGLNLFLIPA DVYASGFTGV AQLLSSVVDQ YAPFYISTGT
LLFLLNIPVG ILGWLKVGKS FTVYSILSVA LTTLFMGILP ETSLSHDILL NAVFGGVISA
VGIGLTLKYG ASTGGLDIVA MVLAKWKDKP VGTYFFILNG IIILTAGLLQ GWEKALYTLV
TLYVTTRVID AIHTRHMKLT AMIVTKKADE IKEAIYGKMV RGITTVPAKG AFTNEQKEMM
IIVITRYELY DLEKIVKEVD PKAFTNIVQT TGIFGFFRKD
