YIY4_SCHPO
ID YIY4_SCHPO Reviewed; 383 AA.
AC Q9UUI8; Q9UU21;
DT 29-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Uncharacterized transporter C22F8.04;
GN ORFNames=SPAC22F8.04;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 73-263, AND SUBCELLULAR
RP LOCATION.
RC STRAIN=ATCC 38364 / 968;
RX PubMed=10759889; DOI=10.1046/j.1365-2443.2000.00317.x;
RA Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T.,
RA Hiraoka Y.;
RT "Large-scale screening of intracellular protein localization in living
RT fission yeast cells by the use of a GFP-fusion genomic DNA library.";
RL Genes Cells 5:169-190(2000).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:10759889}; Multi-
CC pass membrane protein {ECO:0000269|PubMed:10759889}.
CC -!- SIMILARITY: Belongs to the TPT transporter family. {ECO:0000305}.
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DR EMBL; CU329670; CAB52714.1; -; Genomic_DNA.
DR EMBL; AB027863; BAA87167.1; -; Genomic_DNA.
DR PIR; T38194; T38194.
DR RefSeq; NP_594727.1; NM_001020155.2.
DR AlphaFoldDB; Q9UUI8; -.
DR SMR; Q9UUI8; -.
DR BioGRID; 278385; 2.
DR STRING; 4896.SPAC22F8.04.1; -.
DR TCDB; 2.A.7.16.3; the drug/metabolite transporter (dmt) superfamily.
DR iPTMnet; Q9UUI8; -.
DR MaxQB; Q9UUI8; -.
DR PaxDb; Q9UUI8; -.
DR PRIDE; Q9UUI8; -.
DR EnsemblFungi; SPAC22F8.04.1; SPAC22F8.04.1:pep; SPAC22F8.04.
DR GeneID; 2541895; -.
DR KEGG; spo:SPAC22F8.04; -.
DR PomBase; SPAC22F8.04; -.
DR VEuPathDB; FungiDB:SPAC22F8.04; -.
DR eggNOG; KOG1442; Eukaryota.
DR HOGENOM; CLU_044894_0_1_1; -.
DR InParanoid; Q9UUI8; -.
DR OMA; GLQIKYT; -.
DR PhylomeDB; Q9UUI8; -.
DR Reactome; R-SPO-6787639; GDP-fucose biosynthesis.
DR Reactome; R-SPO-727802; Transport of nucleotide sugars.
DR PRO; PR:Q9UUI8; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005794; C:Golgi apparatus; IDA:PomBase.
DR GO; GO:0000139; C:Golgi membrane; EXP:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IBA:GO_Central.
DR GO; GO:0005457; F:GDP-fucose transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0089721; F:phosphoenolpyruvate transmembrane transporter activity; IMP:PomBase.
DR GO; GO:0071917; F:triose-phosphate transmembrane transporter activity; ISM:PomBase.
DR GO; GO:0036085; P:GDP-fucose import into Golgi lumen; IBA:GO_Central.
DR GO; GO:1990536; P:phosphoenolpyruvate transmembrane import into Golgi lumen; IMP:PomBase.
DR GO; GO:0036066; P:protein O-linked fucosylation; IBA:GO_Central.
DR GO; GO:0035436; P:triose phosphate transmembrane transport; ISM:PomBase.
DR InterPro; IPR029666; GDP-fucose_transp.
DR InterPro; IPR004853; Sugar_P_trans_dom.
DR PANTHER; PTHR11132:SF255; PTHR11132:SF255; 1.
DR Pfam; PF03151; TPT; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..383
FT /note="Uncharacterized transporter C22F8.04"
FT /id="PRO_0000116799"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 179..199
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 205..225
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 228..248
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 262..282
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 299..319
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 329..349
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 352..372
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 73..89
FT /note="NAKEPDSENAPVSRLTI -> QCKRARLGKCSCFTTDQ (in Ref. 2;
FT BAA87167)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 383 AA; 42626 MW; DE19628D3CEFF8F9 CRC64;
MSSKLTVNAH YSPLKDEDPL DHIDSQTALD SMETDSTGKS SLYFSKSDDP LSKDIEDGIS
TRKLEEMSVL EANAKEPDSE NAPVSRLTIF FAVSSQIVFA ILVTILNKQA LNIINAPLLM
LSFQMAFTSL MVKMYWRFSS VHFQTLRLAS AIQLKKFIFV KILGIVSKTY CLAFVPVSFY
QISRGLLLPF TILLSFVLLK QKTRLFPFGG CLLVMLGFGF GVRFESHVAP IGIILGVWSS
FTTAIESVAV KHYVHEYPTL DLIYIFSALM SVFCLLLSVA SLELLHTVQE VVGMQAIKFF
IVLILSSLSN FYLNIATFTQ IKVTSPVTYM ISVSARSILQ TLLAVAFLGE TLYGNRIYGV
ILILVGTLLY TLAKEHERRV ASA
