ID   YJ00_YEAST              Reviewed;         745 AA.
AC   P47101; D6VWK3; P87321; Q05848;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   02-NOV-2010, sequence version 3.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=UPF0508 protein YJR030C;
GN   OrderedLocusNames=YJR030C; ORFNames=J1575L;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c, and VP102-10A;
RX   PubMed=8619316; DOI=10.1002/yea.320111208;
RA   Zagulski M., Babinska B., Gromadka R., Migdalski A., Rytka J., Sulicka J.,
RA   Herbert C.J.;
RT   "The sequence of 24.3 kb from chromosome X reveals five complete open
RT   reading frames, all of which correspond to new genes, and a tandem
RT   insertion of a Ty1 transposon.";
RL   Yeast 11:1179-1186(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8641269; DOI=10.1002/j.1460-2075.1996.tb00557.x;
RA   Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C.,
RA   Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D.,
RA   Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J.,
RA   Heumann K., Hilger F., Hollenberg C.P., Huang M.-E., Jacq C.,
RA   Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E.,
RA   Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T.,
RA   Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B.,
RA   Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R.,
RA   Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N.,
RA   To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H.,
RA   von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.;
RT   "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.";
RL   EMBO J. 15:2031-2049(1996).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
CC   -!- SIMILARITY: Belongs to the UPF0508 family. {ECO:0000305}.
CC   -!- CAUTION: This is a truncated version of an UPF0508 family protein.
CC       Strain S288c has a tandem insertion of a Ty1 transposon in position
CC       742, which disrupts the gene coding for this protein and produces two
CC       ORFs YJR030C and YJR025C-A. A contiguous sequence of this protein can
CC       be found in strain YJM789 (AC A6ZPZ1). {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA60727.1; Type=Miscellaneous discrepancy; Note=Contains PCR fragment of strain VP102-10A.; Evidence={ECO:0000305};
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DR   EMBL; X87297; CAA60723.1; -; Genomic_DNA.
DR   EMBL; X87298; CAA60727.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; Z49530; CAA89557.1; -; Genomic_DNA.
DR   EMBL; BK006943; DAA08819.1; -; Genomic_DNA.
DR   PIR; S57048; S57048.
DR   RefSeq; NP_012564.3; NM_001181688.3.
DR   AlphaFoldDB; P47101; -.
DR   BioGRID; 33783; 11.
DR   DIP; DIP-5695N; -.
DR   IntAct; P47101; 3.
DR   MINT; P47101; -.
DR   STRING; 4932.YJR030C; -.
DR   PaxDb; P47101; -.
DR   PRIDE; P47101; -.
DR   EnsemblFungi; YJR030C_mRNA; YJR030C; YJR030C.
DR   GeneID; 853487; -.
DR   KEGG; sce:YJR030C; -.
DR   SGD; S000003791; YJR030C.
DR   VEuPathDB; FungiDB:YJR030C; -.
DR   eggNOG; ENOG502QTEC; Eukaryota.
DR   GeneTree; ENSGT00940000176640; -.
DR   HOGENOM; CLU_338632_0_0_1; -.
DR   InParanoid; P47101; -.
DR   OMA; AQDIQIR; -.
DR   BioCyc; YEAST:G3O-31668-MON; -.
DR   ChiTaRS; RBH2; yeast.
DR   PRO; PR:P47101; -.
DR   Proteomes; UP000002311; Chromosome X.
DR   RNAct; P47101; protein.
DR   GO; GO:0019320; P:hexose catabolic process; IMP:SGD.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..745
FT                   /note="UPF0508 protein YJR030C"
FT                   /id="PRO_0000203090"
FT   VARIANT         742..745
FT                   /note="LRNM -> HVKTKADVWKPSRVGYTDIFSQEYKGIVVAIKFVICSDAEGTLY
FT                   PREYNSRLHDIKRLGRTGLSFTDKKEAYLLEFKNQDVVDHVHKLILPFNTSWQSN (in
FT                   strain: VP102-10A)"
SQ   SEQUENCE   745 AA;  84290 MW;  B287BC72FCE6A211 CRC64;
     MELFNKEEAS FETLLKRLLV VCESHSRYHG SSLDPMVKVG HEMRKISGYL RCILRKHAAN
     HDDMSLTQSI VNSYKSLFKD AQILDLYHNL LFGCMHLLLD ANMSYFRMDS QKLFAVLLFK
     VYYKLRDIFY VTNEVRLGSL ISAFVYKFKS CYDFISCNSL KYGSVRDVIS GEVSLINLPP
     IDSNKVINRA YYRLDVKKLA INNKLVEILE LDNGEIAIFE VLSEKMPYTL QTIDNLFQSL
     ALGNHDLMNV GRSLLFRPFR SGDLDLIRLD DSGAKLKVPI NNSIVLRLTC KDPIQWQEYW
     KHVIRKLFDS TATKEYKRSG SKISQQVYVR SNNPDYTSPK RNDDMPISSV KISDTIHNGR
     TLHRSIPLPG SLSSLIETSN EYPDEESLSI MSERATVSED SDLDTSLKDI ESLSCEKLIE
     LDKSIQVPLS PKYMDTPTLK NIRTASQTFS LESVSPELIE SVASEIDDSE SIISEDGKDK
     RDKDLFDPDI DFYKPTLYRR KSSSLLSIFS KNKKNLTIDI PKNHSRSLFS LPGNQQSVTP
     VSATPHDDNV DETYVSFPLS INTSGGAVYF ENDSVKVSLW NGKSWVPLSK DMLCLSLILS
     GDNETLLIVY KDFEKEKCKL VVKLEPTWKY NRSTAQDVQL RIPSSDFKAS VFGTLHDLTL
     SIRCAQAAKL VNVLQYQLQS SQTSSLSPST TTGTLSTVSS SSCFSRNVTR SSTENSELAN
     MKDSSEYISS SLLLSSVKVR QLRNM