YJ23_SCHPO
ID YJ23_SCHPO Reviewed; 679 AA.
AC Q9USJ3; P78788;
DT 29-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Uncharacterized protein C4B3.03c;
DE Flags: Precursor;
GN ORFNames=SPCC4B3.03c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 199-679.
RC STRAIN=PR745;
RX PubMed=9501991; DOI=10.1093/dnares/4.6.363;
RA Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.;
RT "Identification of open reading frames in Schizosaccharomyces pombe
RT cDNAs.";
RL DNA Res. 4:363-369(1997).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-476; SER-478 AND SER-596, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA13799.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; CU329672; CAB60677.1; -; Genomic_DNA.
DR EMBL; D89137; BAA13799.1; ALT_FRAME; mRNA.
DR PIR; T42414; T42414.
DR PIR; T50445; T50445.
DR RefSeq; NP_588087.1; NM_001023079.2.
DR AlphaFoldDB; Q9USJ3; -.
DR SMR; Q9USJ3; -.
DR BioGRID; 275418; 14.
DR STRING; 4896.SPCC4B3.03c.1; -.
DR iPTMnet; Q9USJ3; -.
DR MaxQB; Q9USJ3; -.
DR PaxDb; Q9USJ3; -.
DR PRIDE; Q9USJ3; -.
DR EnsemblFungi; SPCC4B3.03c.1; SPCC4B3.03c.1:pep; SPCC4B3.03c.
DR GeneID; 2538837; -.
DR KEGG; spo:SPCC4B3.03c; -.
DR PomBase; SPCC4B3.03c; -.
DR VEuPathDB; FungiDB:SPCC4B3.03c; -.
DR eggNOG; KOG2118; Eukaryota.
DR HOGENOM; CLU_011310_3_1_1; -.
DR InParanoid; Q9USJ3; -.
DR OMA; SHMILIS; -.
DR PhylomeDB; Q9USJ3; -.
DR PRO; PR:Q9USJ3; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; -; 1.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR12064; PTHR12064; 2.
DR Pfam; PF01595; DUF21; 1.
DR SUPFAM; SSF54631; SSF54631; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 1: Evidence at protein level;
KW CBS domain; Membrane; Phosphoprotein; Reference proteome; Repeat; Signal;
KW Transmembrane; Transmembrane helix.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..679
FT /note="Uncharacterized protein C4B3.03c"
FT /id="PRO_0000014205"
FT TOPO_DOM 28..65
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 66..86
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 87..121
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 143
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 144..164
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 165..184
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 206..679
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT DOMAIN 58..241
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01193"
FT DOMAIN 260..321
FT /note="CBS 1"
FT DOMAIN 322..387
FT /note="CBS 2"
FT REGION 458..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 638..679
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..557
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..579
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 646..663
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..679
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 476
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 478
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 596
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT CONFLICT 202
FT /note="A -> G (in Ref. 2; BAA13799)"
FT /evidence="ECO:0000305"
FT CONFLICT 215..217
FT /note="TMY -> IMF (in Ref. 2; BAA13799)"
FT /evidence="ECO:0000305"
FT CONFLICT 223
FT /note="K -> R (in Ref. 2; BAA13799)"
FT /evidence="ECO:0000305"
FT CONFLICT 226
FT /note="V -> G (in Ref. 2; BAA13799)"
FT /evidence="ECO:0000305"
FT CONFLICT 233
FT /note="G -> I (in Ref. 2; BAA13799)"
FT /evidence="ECO:0000305"
FT CONFLICT 239..241
FT /note="QDE -> HDD (in Ref. 2; BAA13799)"
FT /evidence="ECO:0000305"
FT CONFLICT 267
FT /note="F -> L (in Ref. 2; BAA13799)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 679 AA; 74306 MW; 61A9BC0F8001A3EA CRC64;
MSLLRIRKAS LYGFSTVFIL LQSYAVAYPL RAFRQNDGIG IAMNPSQDGG FVSAEKDSDF
EYWMKLIISA VLILLGGVFA GLTIGLMGCD DLHLQVLEQS GDASERVHAR KVLKLLRRGK
HWVLVTLLLG NVIVNETLPI VFDSIIGGGW PAVLISTAMI VIFGEVIPQA TCVRYGLSIG
AKLEPIVLFM MYLLWPIAYP TALILDACLG ESQSTMYKKS GLKTLVTLHR DLGIDKLNQD
EVTIITAVLD LREKHAESIM TPIEDVFTLP MDRILDEDLI GEIICAGYSR IPVHKPGFPH
DFIGMLLTKT LIGYDPDDKW PVGKFALATL PQTWPNTSCL DLLNYCQEGK SHMILISNSP
GEPHGAIGVI TLEDIIEELI GEEIIDETDV YIDVHKGLPR VGENNDFWNR MLHRSHLSTM
AALHKSQRSH DLAANEHAPI LNPKNSALNP RLVTNDRVKV KSPSLIQSST GYGSMSQSPS
RSDLPSKISR VNAELQAHGS QRSSIDVSKE NKSSVADGPS SQAHNGPSTQ PPEALPNGTD
PSSSKTTENN GNQQSERTES ADGKKDNSGS ISSNSSKTFT GKRVRLGNVI ESNVVSPDGT
NRIVIEPFER SVDPNNADIV EMVERNGIVV PKVTVTSHED DVDSVHNTPM SVSSTLSVKT
SSSKVPRNKR KRRKGKSKK
