YJ7B_SCHPO
ID YJ7B_SCHPO Reviewed; 471 AA.
AC O74921;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Uncharacterized MFS-type transporter C757.11c;
GN ORFNames=SPCC757.11c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:CAA21236.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2] {ECO:0000305}
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000269|PubMed:16823372}.
CC Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
CC Note=Barrier septum. Cell tip. {ECO:0000255,
CC ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000255}.
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DR EMBL; CU329672; CAA21236.1; -; Genomic_DNA.
DR PIR; T41602; T41602.
DR RefSeq; NP_587686.1; NM_001022681.2.
DR AlphaFoldDB; O74921; -.
DR BioGRID; 275384; 2.
DR STRING; 4896.SPCC757.11c.1; -.
DR iPTMnet; O74921; -.
DR MaxQB; O74921; -.
DR PaxDb; O74921; -.
DR PRIDE; O74921; -.
DR EnsemblFungi; SPCC757.11c.1; SPCC757.11c.1:pep; SPCC757.11c.
DR GeneID; 2538803; -.
DR KEGG; spo:SPCC757.11c; -.
DR PomBase; SPCC757.11c; -.
DR VEuPathDB; FungiDB:SPCC757.11c; -.
DR eggNOG; KOG2325; Eukaryota.
DR HOGENOM; CLU_042172_0_0_1; -.
DR InParanoid; O74921; -.
DR OMA; LACLIDI; -.
DR PhylomeDB; O74921; -.
DR PRO; PR:O74921; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0032153; C:cell division site; HDA:PomBase.
DR GO; GO:0051286; C:cell tip; HDA:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; ISM:PomBase.
DR GO; GO:0055085; P:transmembrane transport; ISM:PomBase.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR SUPFAM; SSF103473; SSF103473; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..471
FT /note="Uncharacterized MFS-type transporter C757.11c"
FT /id="PRO_0000372715"
FT TRANSMEM 48..68
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..140
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 277..297
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 320..340
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 349..369
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 379..399
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 414..434
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 440..460
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 471 AA; 51981 MW; D5E45095E936D68A CRC64;
MEQQSNLEKD LSVSSFLDEK EKSGYKQSVR LVSNDPSASP AATHKPPFIS AALMLLNNTI
LCISFTIVVP TSERFVQHLG GGNGLSGVII GLPTITALVL LYPMLRFSTP KAAKGYTIYR
RPYTMSCISC IIGHIMYALA DKAKSVALIL VSRIFTGVAC TMFLYHKRYF TDKALISIKY
RTSMGVVNSV MATLGLTAGP FIGGLMAKSS MKSQSDIWNE YTSGNWLMAF IWVGLFLFGF
ACFREVLSPQ TDVKEEVVEE KHVINDVKQD TNSKLGFVGC LVIFVVAFSG FSAYFLLNAY
QASVPIYTSM LYNYSSFQAG NFLSLAGIIN VPLLLIFSYL TRYLTDRDII LLGCCLNIVC
MVIHITIHYT GKEFVQPYFI IYTLVFFGSS IANSPSVSLL TKVLHPKYHL IGNVAVQISI
SLSDTVGAIF GGAFRSFSPV VFFAVCLILN VMSVLALLII WKKLKVKLRL A