YJ87_SCHPO
ID YJ87_SCHPO Reviewed; 500 AA.
AC Q12519;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Uncharacterized MFS-type transporter C330.07c;
GN ORFNames=SPCC330.07c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:AAC37421.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=7859562; DOI=10.1007/bf00362286;
RA Zhu J., Carlson D.L., Dubey D.D., Sharma K., Huberman J.A.;
RT "Comparison of the two major ARS elements of the ura4 replication origin
RT region with other ARS elements in the fission yeast, Schizosaccharomyces
RT pombe.";
RL Chromosoma 103:414-422(1994).
RN [2] {ECO:0000312|EMBL:CAA20912.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [3] {ECO:0000305}
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [4] {ECO:0000305}
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-9, AND IDENTIFICATION BY MASS
RP SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000269|PubMed:16823372}.
CC Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
CC Note=Barrier septum. Cell tip. {ECO:0000255,
CC ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000255}.
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DR EMBL; L25861; AAC37421.1; -; Genomic_DNA.
DR EMBL; Z27236; CAA81750.1; -; Genomic_DNA.
DR EMBL; CU329672; CAA20912.1; -; Genomic_DNA.
DR PIR; S47349; S47349.
DR RefSeq; NP_587707.1; NM_001022702.2.
DR AlphaFoldDB; Q12519; -.
DR SMR; Q12519; -.
DR BioGRID; 275610; 7.
DR STRING; 4896.SPCC330.07c.1; -.
DR TCDB; 2.A.1.2.59; the major facilitator superfamily (mfs).
DR iPTMnet; Q12519; -.
DR MaxQB; Q12519; -.
DR PaxDb; Q12519; -.
DR PRIDE; Q12519; -.
DR EnsemblFungi; SPCC330.07c.1; SPCC330.07c.1:pep; SPCC330.07c.
DR GeneID; 2539037; -.
DR KEGG; spo:SPCC330.07c; -.
DR PomBase; SPCC330.07c; -.
DR VEuPathDB; FungiDB:SPCC330.07c; -.
DR eggNOG; KOG2325; Eukaryota.
DR HOGENOM; CLU_042172_0_0_1; -.
DR InParanoid; Q12519; -.
DR OMA; ANWIYLI; -.
DR PhylomeDB; Q12519; -.
DR PRO; PR:Q12519; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0032153; C:cell division site; HDA:PomBase.
DR GO; GO:0051286; C:cell tip; HDA:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; ISM:PomBase.
DR GO; GO:0034220; P:ion transmembrane transport; IEA:UniProt.
DR GO; GO:0055085; P:transmembrane transport; ISM:PomBase.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
PE 1: Evidence at protein level;
KW Golgi apparatus; Membrane; Phosphoprotein; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..500
FT /note="Uncharacterized MFS-type transporter C330.07c"
FT /id="PRO_0000372716"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 126..146
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 156..176
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 183..203
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 261..281
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 312..332
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 351..371
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 380..400
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 408..428
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 445..465
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 471..491
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 9
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 500 AA; 56109 MW; F2ED3093F544DE1F CRC64;
MEPSQRSGSF SSISRRRSRV DSRPTYFKVT SKDLGFVDQV SEEYEFYTYP KKASEVESVT
ETFQSNRSSL VPTYPVDENA NKLPPKVSIA FILINSLMSD MSLAVALPTS ASYTQSLGGT
NAFSGLVIGI PTLISLIFLY PMLCFANPKS ANGYTLYFRP MVVSSFAHIF GHLLYCMAYR
ANWIYLILIG RMLNGIGFTT FLYHKKYTTD KLLVGQNRRT FLATMNILAQ TLGFMAGPFL
GGILAKATIH SKNAVWNQYT VASWVMLFMW FFYMLTIIFF FKEVTADKSE KVSQQKENDD
EDRPKLSWKH KFLLFFLAEV AFIAYFTVNG YQASISIYTG KLYNYDAFQS GNFIALSALI
VAPFILASSF LSRWLEDRHI MLGGLFLGIL AVAIHLVLDA VHKLPMQVYF FLYSLMIYGY
SIGSAPLISL SSKQLHPRHH NTASIVVQVG VSLSNTFGSI CGGAIYNITT VGFISLCLGL
AAVVYMQLIF MWGSLKCKTH
