YJB6_YEAST
ID YJB6_YEAST Reviewed; 561 AA.
AC P47072; D6VWG2; P47071; Q86ZR5;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 07-MAR-2006, sequence version 2.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=Uncharacterized protein YJL016W;
GN OrderedLocusNames=YJL016W; ORFNames=J1320, J1326, YJL017W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8641269; DOI=10.1002/j.1460-2075.1996.tb00557.x;
RA Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C.,
RA Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D.,
RA Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J.,
RA Heumann K., Hilger F., Hollenberg C.P., Huang M.-E., Jacq C.,
RA Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E.,
RA Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T.,
RA Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R.,
RA Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N.,
RA To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H.,
RA von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.;
RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.";
RL EMBO J. 15:2031-2049(1996).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 295-377, AND IDENTIFICATION OF
RP FRAMESHIFT.
RC STRAIN=ATCC 204511 / S288c / AB972;
RX PubMed=12844361; DOI=10.1186/gb-2003-4-7-r45;
RA Brachat S., Dietrich F.S., Voegeli S., Zhang Z., Stuart L., Lerch A.,
RA Gates K., Gaffney T.D., Philippsen P.;
RT "Reinvestigation of the Saccharomyces cerevisiae genome annotation by
RT comparison to the genome of a related fungus: Ashbya gossypii.";
RL Genome Biol. 4:R45.1-R45.13(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 391-561.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [6]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [7]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-514, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT "A multidimensional chromatography technology for in-depth phosphoproteome
RT analysis.";
RL Mol. Cell. Proteomics 7:1389-1396(2008).
RN [8]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-514, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19779198; DOI=10.1126/science.1172867;
RA Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT into evolution.";
RL Science 325:1682-1686(2009).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 3360 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA89306.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=CAA89308.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; Z49291; CAA89306.1; ALT_FRAME; Genomic_DNA.
DR EMBL; Z49292; CAA89308.1; ALT_FRAME; Genomic_DNA.
DR EMBL; AY260898; AAP21766.1; -; Genomic_DNA.
DR EMBL; AY692698; AAT92717.1; -; Genomic_DNA.
DR EMBL; BK006943; DAA08778.1; -; Genomic_DNA.
DR PIR; S56787; S56787.
DR PIR; S56788; S56788.
DR RefSeq; NP_012518.2; NM_001181450.1.
DR AlphaFoldDB; P47072; -.
DR BioGRID; 33740; 39.
DR DIP; DIP-4907N; -.
DR IntAct; P47072; 7.
DR MINT; P47072; -.
DR STRING; 4932.YJL016W; -.
DR iPTMnet; P47072; -.
DR MaxQB; P47072; -.
DR PaxDb; P47072; -.
DR PRIDE; P47072; -.
DR TopDownProteomics; P47072; -.
DR EnsemblFungi; YJL016W_mRNA; YJL016W; YJL016W.
DR GeneID; 853436; -.
DR KEGG; sce:YJL016W; -.
DR SGD; S000003553; YJL016W.
DR VEuPathDB; FungiDB:YJL016W; -.
DR eggNOG; ENOG502QTIE; Eukaryota.
DR GeneTree; ENSGT00940000176380; -.
DR HOGENOM; CLU_017094_2_0_1; -.
DR InParanoid; P47072; -.
DR OMA; LIKPIPH; -.
DR BioCyc; YEAST:G3O-31490-MON; -.
DR PRO; PR:P47072; -.
DR Proteomes; UP000002311; Chromosome X.
DR RNAct; P47072; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
PE 1: Evidence at protein level;
KW Cytoplasm; Phosphoprotein; Reference proteome.
FT CHAIN 1..561
FT /note="Uncharacterized protein YJL016W"
FT /id="PRO_0000203075"
FT REGION 314..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 514
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:18407956,
FT ECO:0007744|PubMed:19779198"
SQ SEQUENCE 561 AA; 63207 MW; 21D1541BCFEFDFF6 CRC64;
MGILDSLKKP VNIKSSLPKF SRSATSINLS SHPVSSRSFL ELPPELFSIT KPIFKLLQAH
ANKIYFQSSD AEAVWNVKDS SGHVFEAESI SLLGSHIIIT NSSVQVADVA IIDSPSNINQ
CEISSVGEFL QFNNGQLSIT CNDFGLLEKF KRLCMISIFE FISIYKALTG TVISSYGLRM
SDMHIILNSP FNFKDWCEVY LDGQGWVKVW CHIDKVSKTN NSKSSSDNDA KGKYQIRFYR
DDKSTSSKNC VFFIPDNEYV QDIFFYNINA AEPSKNMNDF FQGLQMIKLV GNVRFCSDTD
FNDVVDSGSI YSSANNGSGD SSSTALNNES PNTTPKSRTF FSPKGHRRNS SHVSSLTSRS
TKKPITNFTT RTNGLLIRPL PHHGVHHLEA MIRFIIPLMD CARLYGRPVQ FKTERTDINS
LMFGLPKLPS VDYFAEEEIA HLMTQEFNPL KEKDTDDTMA LTMSRFSSYL QERMTKVSKR
NTELNFRTFS DVMGMYNTTR DHSKLNCMSD KDNSVKEFSL SDKSNVSSET TNMMNQLQVN
AHEYKSSMCE RPIVASTSPI A