YJBQ_BACSU
ID YJBQ_BACSU Reviewed; 614 AA.
AC O31615;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Putative Na(+)/H(+) antiporter YjbQ;
GN Name=yjbQ; OrderedLocusNames=BSU11640;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
CC -!- FUNCTION: Probable Na(+)/H(+) antiporter. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. {ECO:0000305}.
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DR EMBL; AL009126; CAB13021.1; -; Genomic_DNA.
DR PIR; A69845; A69845.
DR RefSeq; NP_389046.1; NC_000964.3.
DR RefSeq; WP_003232910.1; NZ_JNCM01000035.1.
DR AlphaFoldDB; O31615; -.
DR SMR; O31615; -.
DR STRING; 224308.BSU11640; -.
DR PaxDb; O31615; -.
DR PRIDE; O31615; -.
DR EnsemblBacteria; CAB13021; CAB13021; BSU_11640.
DR GeneID; 939371; -.
DR KEGG; bsu:BSU11640; -.
DR PATRIC; fig|224308.179.peg.1253; -.
DR eggNOG; COG0475; Bacteria.
DR eggNOG; COG0569; Bacteria.
DR InParanoid; O31615; -.
DR OMA; PYLWFAK; -.
DR PhylomeDB; O31615; -.
DR BioCyc; BSUB:BSU11640-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.30.70.1450; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02080; TrkA_C; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF116726; SSF116726; 1.
DR SUPFAM; SSF51735; SSF51735; 1.
DR PROSITE; PS51202; RCK_C; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 3: Inferred from homology;
KW Antiport; Cell membrane; Ion transport; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..614
FT /note="Putative Na(+)/H(+) antiporter YjbQ"
FT /id="PRO_0000360057"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 225..244
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 248..267
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 282..302
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 307..327
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 338..358
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 368..388
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 403..525
FT /note="RCK N-terminal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00543"
FT DOMAIN 533..614
FT /note="RCK C-terminal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
SQ SEQUENCE 614 AA; 67468 MW; EAAAE1850799163B CRC64;
MAHTSVASLV VVLIVAFLTP ILLHRFKLSI PVVVAEIIMG LIIGKSGLNL VVEGDTWLQT
LSMLGFIFLM FLSGLEIDFS SFEKGKKKQF LPNGKEAPNT FAAASVIFVG IFILSLLLSY
GFVLAGFIQN AFLMTLIIST ISLGVVVPTL KEERIMNSNI GQIILLVAVI ADLATMILLA
VFSSLYGEDS GNMWLLMILF AAGVVLYFFG RVFKHRSFVQ SMSKGTIQIG TRAIFTLIIV
LVALSESLGA ENILGAFLAG VLVSLLSPNK ELVQQLDSFG YGFLIPIFFV MVGVKLDIWT
LFQDKTILIM IPLLLLALLV SKIIPVMYLK KWYDNRTIFA SGFLLTSTLS LVIAAATIGQ
QLHVISTNMS GALILVAVIA SIFTPICFKK LYKREEQPEE KKTITFIGAN QMTLPVTLEL
PEEEYDVRVV HVYQENAEEK LSESVFAVET ISDYEHETLE SLGIFETDIL VVATGNEDMN
ADIALLAKDK GTERVIASVG SPEHEAALKE QGISIFSILL STKTLLRALI EAPGVMKLLT
NQESSLYQIN MENSKYDGVI LREFPLTGDV IFVRIFRGVD SIVPHGDTRL KLGDRLIVTG
SRGYVTDLKK TLEG
