ID   YJCD_BACSU              Reviewed;         759 AA.
AC   O31626;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Putative ATP-dependent DNA helicase YjcD;
DE            EC=3.6.4.12;
GN   Name=yjcD; OrderedLocusNames=BSU11820;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [2]
RP   POSSIBLE FUNCTION AS HELICASE.
RC   STRAIN=168 / YB886 / BG214;
RX   PubMed=11544244; DOI=10.1128/jb.183.19.5772-5777.2001;
RA   Carrasco B., Fernandez S., Petit M.-A., Alonso J.C.;
RT   "Genetic recombination in Bacillus subtilis 168: effect of delta helD on
RT   DNA repair and homologous recombination.";
RL   J. Bacteriol. 183:5772-5777(2001).
CC   -!- FUNCTION: May be involved in the generation of recombinogenic
CC       substrates for the subsequent action of RecA.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AL009126; CAB13039.3; -; Genomic_DNA.
DR   PIR; D69846; D69846.
DR   RefSeq; NP_389064.2; NC_000964.3.
DR   RefSeq; WP_003245380.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; O31626; -.
DR   SMR; O31626; -.
DR   STRING; 224308.BSU11820; -.
DR   PaxDb; O31626; -.
DR   PRIDE; O31626; -.
DR   EnsemblBacteria; CAB13039; CAB13039; BSU_11820.
DR   GeneID; 939813; -.
DR   KEGG; bsu:BSU11820; -.
DR   PATRIC; fig|224308.179.peg.1273; -.
DR   eggNOG; COG0210; Bacteria.
DR   InParanoid; O31626; -.
DR   OMA; YRHFVVD; -.
DR   BioCyc; BSUB:BSU11820-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0033202; C:DNA helicase complex; IBA:GO_Central.
DR   GO; GO:0043138; F:3'-5' DNA helicase activity; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000725; P:recombinational repair; IBA:GO_Central.
DR   Gene3D; 1.10.10.160; -; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070; PTHR11070; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Cytoplasm; DNA-binding; Helicase; Hydrolase;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN           1..759
FT                   /note="Putative ATP-dependent DNA helicase YjcD"
FT                   /id="PRO_0000361274"
FT   DOMAIN          134..413
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00560"
FT   DOMAIN          414..676
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00617"
FT   REGION          68..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        68..88
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         158..163
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00560"
FT   BINDING         411
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   759 AA;  86976 MW;  8FEDE8CFFFA1F5CE CRC64;
     MKCARLNDRI IHLHTYSREH YQFLFEEGIK GHLFCSHCGK PVLLRLNIAD PPEFIHRQPG
     DFPACEEACE PKPSKEGKKE DDQESGVIRL PKGKAIAADP SPAVTEWHRP RSIKPGTPFV
     PKTIEPDTSL FPSVGLNTDQ LKAVTETEGP LLVLAGAGSG KTRVLTARAA HMIEHLGIPP
     ENMLLVTFTT KAVAEMKERM ANQYGLQPAK VRRIVTGTFH SLFYKILYHS NSAKWNGEHL
     LKMEWQREQY IKKALYEEGI DEKESPVDQA LQQIGFWKNT YVPNERIPLK DEWEKQVYRL
     YEHYERQKKE HSQFDFDDMA SACYELFIER PDLLEQYQSR FTYILIDEFQ DINPVQYKIM
     QMLASPEQNL CCVGDDDQSI YAFRGSNPSF ILDFQKDYPG AKTIYLTANY RSTHPIVSSA
     DIVVKKNKNR YAKTLEAARD DIQVPVLFYP YDEEEEATMV VSDIKEKIQN GASPEDFAVL
     YRTNSGGRAI YERLHQSSIP YTADRGVQSF YSRRIVRQIL AYLYASQNED DTEAIKHLLP
     ALFLKQSALN TLKALSITED CTMIKALAKL PDLKPFQLDK IKKIVPFFAS LRTMKPVEAI
     TFAEGKMGFS EYLKKRGNEG NKLEKGSDDL RDIKVVAKKF KTIPDFLAHV DHMRAAEKNR
     TDEHGVQLMT IHRSKGLEFK TVYVLGTVDG SIPHDFSLET ARKGDEAALE EERRLLYVAM
     TRAKQHLYLS CPANRRGKTA NRSRFLYPLL QKARQPLHH