YJCD_SCHPO
ID YJCD_SCHPO Reviewed; 339 AA.
AC O74959;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Uncharacterized oxidoreductase C736.13;
DE EC=1.-.-.-;
GN ORFNames=SPCC736.13;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000305}.
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DR EMBL; CU329672; CAA19277.1; -; Genomic_DNA.
DR PIR; T41570; T41570.
DR RefSeq; NP_587784.1; NM_001022777.2.
DR AlphaFoldDB; O74959; -.
DR SMR; O74959; -.
DR BioGRID; 276126; 11.
DR STRING; 4896.SPCC736.13.1; -.
DR MaxQB; O74959; -.
DR PaxDb; O74959; -.
DR EnsemblFungi; SPCC736.13.1; SPCC736.13.1:pep; SPCC736.13.
DR GeneID; 2539566; -.
DR KEGG; spo:SPCC736.13; -.
DR PomBase; SPCC736.13; -.
DR VEuPathDB; FungiDB:SPCC736.13; -.
DR eggNOG; KOG1208; Eukaryota.
DR HOGENOM; CLU_010194_44_6_1; -.
DR InParanoid; O74959; -.
DR OMA; NRPVVGW; -.
DR PhylomeDB; O74959; -.
DR Reactome; R-SPO-5365859; RA biosynthesis pathway.
DR PRO; PR:O74959; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0016491; F:oxidoreductase activity; ISM:PomBase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002347; SDR_fam.
DR Pfam; PF00106; adh_short; 1.
DR PRINTS; PR00081; GDHRDH.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 3: Inferred from homology;
KW Oxidoreductase; Reference proteome.
FT CHAIN 1..339
FT /note="Uncharacterized oxidoreductase C736.13"
FT /id="PRO_0000374031"
FT ACT_SITE 213
FT /note="Proton acceptor"
FT /evidence="ECO:0000250"
FT BINDING 49..55
FT /ligand="NADP(+)"
FT /ligand_id="ChEBI:CHEBI:58349"
FT /evidence="ECO:0000250"
FT BINDING 184
FT /ligand="substrate"
FT /evidence="ECO:0000250"
SQ SEQUENCE 339 AA; 38513 MW; 5E1D4AE1E3EE2855 CRC64;
MSYSFQGLLN RVNESAIVNT LKEYTGLNTP KWTFNDIPDL TGKVALVTGS SGGIGYVTAL
ELARKGAKVY LAGRNEEKYQ KVMKQIHDEV RHSKIRFLRL DLLDFESVYQ AAESFIAKEE
KLHILVNNAG IMNPPFELTK DGYELQIQTN YLSHYLFTEL LLPTLRRTAE ECRPGDVRIV
HVASIAYLQA PYSGIYFPDL NLPHVLLGTF ARYGQSKYAQ ILYSIALAKR LEKYGIYSVS
LHPGVIRTEL TRYSPTFALK LLEKSVFQYL LLDPIRGAMT SLYAATSPEI SKEHLNGAYF
TAIAQRGILH RAHDDAFVEE LYRYTHKIFE DLKYLAPSP