ID   CBIM2_METLZ             Reviewed;         231 AA.
AC   A2SSE8;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Putative cobalt transport protein CbiM 2 {ECO:0000255|HAMAP-Rule:MF_01462};
DE   AltName: Full=Energy-coupling factor transporter probable substrate-capture protein CbiM 2 {ECO:0000255|HAMAP-Rule:MF_01462};
DE            Short=ECF transporter S component CbiM 2 {ECO:0000255|HAMAP-Rule:MF_01462};
GN   Name=cbiM2 {ECO:0000255|HAMAP-Rule:MF_01462}; OrderedLocusNames=Mlab_1085;
OS   Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanocorpusculaceae; Methanocorpusculum.
OX   NCBI_TaxID=410358;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43576 / DSM 4855 / Z;
RX   PubMed=21304657; DOI=10.4056/sigs.35575;
RA   Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A.,
RA   Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L.,
RA   Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT   "Complete genome sequence of Methanocorpusculum labreanum type strain Z.";
RL   Stand. Genomic Sci. 1:197-203(2009).
CC   -!- FUNCTION: Part of the energy-coupling factor (ECF) transporter complex
CC       CbiMNOQ involved in cobalt import. {ECO:0000255|HAMAP-Rule:MF_01462}.
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01462}.
CC   -!- SUBUNIT: Forms an energy-coupling factor (ECF) transporter complex
CC       composed of an ATP-binding protein (A component, CbiO), a transmembrane
CC       protein (T component, CbiQ) and 2 possible substrate-capture proteins
CC       (S components, CbiM and CbiN) of unknown stoichimetry.
CC       {ECO:0000255|HAMAP-Rule:MF_01462}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01462};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01462}.
CC   -!- SIMILARITY: Belongs to the CbiM family. {ECO:0000255|HAMAP-
CC       Rule:MF_01462}.
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DR   EMBL; CP000559; ABN07254.1; -; Genomic_DNA.
DR   RefSeq; WP_011833457.1; NC_008942.1.
DR   AlphaFoldDB; A2SSE8; -.
DR   SMR; A2SSE8; -.
DR   STRING; 410358.Mlab_1085; -.
DR   EnsemblBacteria; ABN07254; ABN07254; Mlab_1085.
DR   GeneID; 4796158; -.
DR   KEGG; mla:Mlab_1085; -.
DR   eggNOG; arCOG02248; Archaea.
DR   HOGENOM; CLU_052508_3_0_2; -.
DR   OMA; ANVFSMG; -.
DR   OrthoDB; 94360at2157; -.
DR   UniPathway; UPA00148; -.
DR   Proteomes; UP000000365; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_01462; CbiM; 1.
DR   InterPro; IPR018024; CbiM.
DR   InterPro; IPR002751; CbiM/NikMN.
DR   PANTHER; PTHR43627; PTHR43627; 1.
DR   Pfam; PF01891; CbiM; 1.
DR   TIGRFAMs; TIGR00123; cbiM; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Cobalamin biosynthesis; Cobalt; Cobalt transport;
KW   Ion transport; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..231
FT                   /note="Putative cobalt transport protein CbiM 2"
FT                   /id="PRO_0000411156"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01462"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01462"
FT   TRANSMEM        75..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01462"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01462"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01462"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01462"
SQ   SEQUENCE   231 AA;  24570 MW;  CA29976806E9BC06 CRC64;
     MHIMEGYLPI GWCIFWAVLS APFVIYGIWK MTKMIQEDRR VLPLMAVCGA FVFVLSALKI
     PSVTGSCSHP TGTGLSAAFF GPFITSVLGT IVLLFQALLL AHGGLTTLGA NVFSMAIAGP
     FIAWLVFVGL RKTGKVGIGV AVFITAAVAN LVTYTVTSLQ LALVFPVEGS ILNAFIAFAG
     IFAVTQIPLA IIEGIICALV AKYIVRVKPE ILKKLGIIQD EEIAKIQGEA V