YJE9_YEAST
ID YJE9_YEAST Reviewed; 450 AA.
AC P47048; D6VWD4;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Uncharacterized protein YJL049W;
GN OrderedLocusNames=YJL049W; ORFNames=J1162;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8641269; DOI=10.1002/j.1460-2075.1996.tb00557.x;
RA Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C.,
RA Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D.,
RA Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J.,
RA Heumann K., Hilger F., Hollenberg C.P., Huang M.-E., Jacq C.,
RA Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E.,
RA Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T.,
RA Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R.,
RA Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N.,
RA To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H.,
RA von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.;
RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.";
RL EMBO J. 15:2031-2049(1996).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT "A multidimensional chromatography technology for in-depth phosphoproteome
RT analysis.";
RL Mol. Cell. Proteomics 7:1389-1396(2008).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-terminal
RT acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC -!- MISCELLANEOUS: Present with 2530 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; Z49324; CAA89340.1; -; Genomic_DNA.
DR EMBL; AY692694; AAT92713.1; -; Genomic_DNA.
DR EMBL; BK006943; DAA08750.1; -; Genomic_DNA.
DR PIR; S56821; S56821.
DR RefSeq; NP_012486.3; NM_001181482.3.
DR AlphaFoldDB; P47048; -.
DR SMR; P47048; -.
DR BioGRID; 33706; 213.
DR IntAct; P47048; 5.
DR STRING; 4932.YJL049W; -.
DR iPTMnet; P47048; -.
DR MaxQB; P47048; -.
DR PaxDb; P47048; -.
DR PRIDE; P47048; -.
DR EnsemblFungi; YJL049W_mRNA; YJL049W; YJL049W.
DR GeneID; 853398; -.
DR KEGG; sce:YJL049W; -.
DR SGD; S000003585; YJL049W.
DR VEuPathDB; FungiDB:YJL049W; -.
DR eggNOG; KOG2911; Eukaryota.
DR HOGENOM; CLU_021165_2_0_1; -.
DR InParanoid; P47048; -.
DR OMA; NEQMATT; -.
DR BioCyc; YEAST:G3O-31513-MON; -.
DR PRO; PR:P47048; -.
DR Proteomes; UP000002311; Chromosome X.
DR RNAct; P47048; protein.
DR GO; GO:0000815; C:ESCRT III complex; IBA:GO_Central.
DR GO; GO:0005771; C:multivesicular body; IBA:GO_Central.
DR GO; GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IBA:GO_Central.
DR GO; GO:0006900; P:vesicle budding from membrane; IBA:GO_Central.
DR InterPro; IPR005024; Snf7_fam.
DR PANTHER; PTHR22761; PTHR22761; 1.
DR Pfam; PF03357; Snf7; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..450
FT /note="Uncharacterized protein YJL049W"
FT /id="PRO_0000203065"
FT REGION 387..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..415
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 450 AA; 52849 MW; 20960EEA81E92DFC CRC64;
MKVDLPESRL PSLYRDFRPL KDLNPDGYEA NISTWRDFFL QQYISNSNRI IFTIGTRTLQ
ELTHEVYGVP KSIDIAIDVL VNEGNLIPME LFNLGGMYTD NSRKGFWKWV RSWKESTNMY
KSRKDETNFY LREDKFIIKA NLEKEYQRFH ELLKRSVFME ASSITDLVFT RNEFVTTESL
QSFFSTYDEE TKNVFLHFIE NYKHIIVSKD NVIKVIAAEV EDITSRFSKG ITENDLRIAS
VKVGIININK QITRLRKEIN ESNIKLRGPE FNELPKRIRI EYKQARLLSE KHLSRLLKFQ
NNLAQVRTQI DTSATNAVLI QTLSESNEVI KSINGYIGST EKVEDLLDEI KEGHDRTEEV
NDLLAHYNKG QDEEAEEEIE RELEQLELDE KNNNKEENKN QDLHEPKESS SEDLLKRLNN
LKINTNEGPV QDNENHDNEI RKIMMEEQPR