YJEM_SALTI
ID YJEM_SALTI Reviewed; 500 AA.
AC P0A2N5; Q9ZJ11;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=Inner membrane transporter YjeM;
GN Name=yjeM; OrderedLocusNames=STY4705, t4397;
OS Salmonella typhi.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90370;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT18;
RX PubMed=11677608; DOI=10.1038/35101607;
RA Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA Barrell B.G.;
RT "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT serovar Typhi CT18.";
RL Nature 413:848-852(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700931 / Ty2;
RX PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT CT18.";
RL J. Bacteriol. 185:2330-2337(2003).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. {ECO:0000305}.
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DR EMBL; AL513382; CAD06825.1; -; Genomic_DNA.
DR EMBL; AE014613; AAO71848.1; -; Genomic_DNA.
DR RefSeq; NP_458784.1; NC_003198.1.
DR RefSeq; WP_000149876.1; NZ_WSUR01000012.1.
DR AlphaFoldDB; P0A2N5; -.
DR SMR; P0A2N5; -.
DR STRING; 220341.16505475; -.
DR EnsemblBacteria; AAO71848; AAO71848; t4397.
DR KEGG; stt:t4397; -.
DR KEGG; sty:STY4705; -.
DR PATRIC; fig|220341.7.peg.4806; -.
DR eggNOG; COG0531; Bacteria.
DR HOGENOM; CLU_020854_2_1_6; -.
DR OMA; FMWFASY; -.
DR Proteomes; UP000000541; Chromosome.
DR Proteomes; UP000002670; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002293; AA/rel_permease1.
DR Pfam; PF13520; AA_permease_2; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..500
FT /note="Inner membrane transporter YjeM"
FT /id="PRO_0000213047"
FT TOPO_DOM 1..10
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 32..37
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 59..83
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 105..124
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 125..145
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 146..163
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 185..209
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 231..243
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 265..308
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 309..329
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 330..361
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 362..382
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 383..394
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 395..415
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 416..433
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 434..454
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 455..462
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 463..483
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 484..500
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 500 AA; 54460 MW; C737D037B631F52A CRC64;
MTHTIKKMSL IGLILMIFTS VFGFANSPSA FYLMGYSAIP WYIFSALLFF IPFALMMAEM
GSAYRKEEGG IYSWMNNSVG PRYAFIGTFM WFSSYVIWMV STAAKIWVPF STFVFGADMT
QHWRIAGLEP TQVVGLLAVG WMILVTCVAA RGINKIARIT AVGGIAVMCL NLVLLLVSVA
ILLLNGGHFA QEINFTSSPN PGYHSGLAML SFVVFAIFAY GGIEAVGGLV DKTEKPEKNF
AKGIVFAAIV ISIGYSLAIF LWGVSTNWQQ ILSNSAVNLG NITYILMSSL GTTLGNALNL
SPEAAMTVGV WFARITGLSM FLAYTGAFFT LSYSPLKAII QGTPKALWPA PMTTLNANGM
PATAMWLQCV LVSLFILLVS FGGDTASAFY NKLTLMANVS MTLPYLFLAL AFPFFKARQD
LERPFVLFKT KASTLVATGV VVLVVTFANV FTIIQPVIEA GDWDSALWMI GGPIFFSLLA
MAIYQNYSSR MSADPEWAAE
