YJFF_ECOLI
ID YJFF_ECOLI Reviewed; 331 AA.
AC P37772; Q2M675;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 14-AUG-2001, sequence version 3.
DT 03-AUG-2022, entry version 151.
DE RecName: Full=Inner membrane ABC transporter permease protein YjfF;
GN Name=yjfF; OrderedLocusNames=b4231, JW5754;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=7610040; DOI=10.1093/nar/23.12.2105;
RA Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.;
RT "Analysis of the Escherichia coli genome VI: DNA sequence of the region
RT from 92.8 through 100 minutes.";
RL Nucleic Acids Res. 23:2105-2119(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 257-331.
RX PubMed=2843822; DOI=10.1093/nar/16.17.8707;
RA Hamilton W.D.O., Harrison D.A., Dyer T.A.;
RT "Sequence of the Escherichia coli fructose-1,6-bisphosphatase gene.";
RL Nucleic Acids Res. 16:8707-8707(1988).
RN [5]
RP IDENTIFICATION.
RX PubMed=7984428; DOI=10.1093/nar/22.22.4756;
RA Borodovsky M., Rudd K.E., Koonin E.V.;
RT "Intrinsic and extrinsic approaches for detecting genes in a bacterial
RT genome.";
RL Nucleic Acids Res. 22:4756-4767(1994).
RN [6]
RP SUBCELLULAR LOCATION, AND TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
RN [7]
RP FUNCTION, AND SUBUNIT.
RC STRAIN=K12;
RX PubMed=19744923; DOI=10.1074/jbc.m109.054296;
RA Horler R.S., Muller A., Williamson D.C., Potts J.R., Wilson K.S.,
RA Thomas G.H.;
RT "Furanose-specific sugar transport: characterization of a bacterial
RT galactofuranose-binding protein.";
RL J. Biol. Chem. 284:31156-31163(2009).
CC -!- FUNCTION: Part of the ABC transporter complex YtfQRT-YjfF involved in
CC galactofuranose transport (Probable). Probably responsible for the
CC translocation of the substrate across the membrane (Probable).
CC {ECO:0000305, ECO:0000305|PubMed:19744923}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (YtfR),
CC two transmembrane proteins (YtfT and YjfF) and a solute-binding protein
CC (YtfQ). {ECO:0000305|PubMed:19744923}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. AraH/RbsC subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA97128.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; U14003; AAA97128.1; ALT_INIT; Genomic_DNA.
DR EMBL; U00096; AAC77188.2; -; Genomic_DNA.
DR EMBL; AP009048; BAE78231.1; -; Genomic_DNA.
DR EMBL; X12545; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; S56457; S56457.
DR RefSeq; NP_418652.2; NC_000913.3.
DR RefSeq; WP_000596014.1; NZ_LN832404.1.
DR AlphaFoldDB; P37772; -.
DR BioGRID; 4259315; 24.
DR ComplexPortal; CPX-4323; Galactofuranose ABC transporter complex.
DR STRING; 511145.b4231; -.
DR TCDB; 3.A.1.2.25; the atp-binding cassette (abc) superfamily.
DR PaxDb; P37772; -.
DR PRIDE; P37772; -.
DR EnsemblBacteria; AAC77188; AAC77188; b4231.
DR EnsemblBacteria; BAE78231; BAE78231; BAE78231.
DR GeneID; 948754; -.
DR KEGG; ecj:JW5754; -.
DR KEGG; eco:b4231; -.
DR PATRIC; fig|1411691.4.peg.2471; -.
DR EchoBASE; EB2334; -.
DR eggNOG; COG1172; Bacteria.
DR HOGENOM; CLU_028880_3_3_6; -.
DR InParanoid; P37772; -.
DR OMA; IGFWGIS; -.
DR PhylomeDB; P37772; -.
DR BioCyc; EcoCyc:YJFF-MON; -.
DR BioCyc; MetaCyc:YJFF-MON; -.
DR PRO; PR:P37772; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; IC:ComplexPortal.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005887; C:integral component of plasma membrane; ISM:EcoCyc.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0140271; P:hexose import across plasma membrane; IC:ComplexPortal.
DR InterPro; IPR001851; ABC_transp_permease.
DR Pfam; PF02653; BPD_transp_2; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Sugar transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..331
FT /note="Inner membrane ABC transporter permease protein
FT YjfF"
FT /id="PRO_0000060260"
FT TOPO_DOM 1..5
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 27..42
FT /note="Periplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 64..88
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 89..109
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 110..113
FT /note="Periplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 114..134
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 135..159
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 160..180
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 181..222
FT /note="Periplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 244..250
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 251..271
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 272..294
FT /note="Periplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 295..315
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 316..331
FT /note="Cytoplasmic"
FT /evidence="ECO:0000269|PubMed:15919996"
FT CONFLICT 257
FT /note="L -> V (in Ref. 4; X12545)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 331 AA; 34978 MW; A30435AA393D6C9F CRC64;
MIKRNLPLMI TIGVFVLGYL YCLTQFPGFA STRVICNILT DNAFLGIIAV GMTFVILSGG
IDLSVGSVIA FTGVFLAKVI GDFGLSPLLA FPLVLVMGCA FGAFMGLLID ALKIPAFIIT
LAGMFFLRGV SYLVSEESIP INHPIYDTLS SLAWKIPGGG RLSAMGLLML AVVVIGIFLA
HRTRFGNQVY AIGGNATSAN LMGISTRSTT IRIYMLSTGL ATLAGIVFSI YTQAGYALAG
VGVELDAIAS VVIGGTLLSG GVGTVLGTLF GVAIQGLIQT YINFDGTLSS WWTKIAIGIL
LFIFIALQRG LTVLWENRQS SPVTRVNIAQ Q
