YJIB_BACSU
ID YJIB_BACSU Reviewed; 396 AA.
AC O34374;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Putative cytochrome P450 YjiB;
DE EC=1.14.-.-;
GN Name=yjiB; OrderedLocusNames=BSU12210;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RA Rivolta C., Soldo B., Lazarevic V., Joris B., Mauel C., Karamata D.;
RT "A 35.7 kb DNA fragment from Bacillus subtilis chromosome containing a
RT putative 12.3 kb operon involved in hexuronate catabolism and a perfect
RT catabolite-responsive element.";
RL Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR EMBL; AF015825; AAC46317.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB13078.1; -; Genomic_DNA.
DR PIR; B69851; B69851.
DR RefSeq; NP_389103.1; NC_000964.3.
DR RefSeq; WP_003232789.1; NZ_JNCM01000035.1.
DR PDB; 4RM4; X-ray; 1.77 A; A=1-396.
DR PDBsum; 4RM4; -.
DR AlphaFoldDB; O34374; -.
DR SMR; O34374; -.
DR STRING; 224308.BSU12210; -.
DR PaxDb; O34374; -.
DR PRIDE; O34374; -.
DR EnsemblBacteria; CAB13078; CAB13078; BSU_12210.
DR GeneID; 936452; -.
DR KEGG; bsu:BSU12210; -.
DR PATRIC; fig|224308.179.peg.1319; -.
DR eggNOG; COG2124; Bacteria.
DR InParanoid; O34374; -.
DR OMA; FQRTATQ; -.
DR PhylomeDB; O34374; -.
DR BioCyc; BSUB:BSU12210-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0036199; F:cholest-4-en-3-one 26-monooxygenase activity; IBA:GO_Central.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0008395; F:steroid hydroxylase activity; IBA:GO_Central.
DR GO; GO:0006707; P:cholesterol catabolic process; IBA:GO_Central.
DR Gene3D; 1.10.630.10; -; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR002397; Cyt_P450_B.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR036396; Cyt_P450_sf.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00359; BP450.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; SSF48264; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase;
KW Reference proteome.
FT CHAIN 1..396
FT /note="Putative cytochrome P450 YjiB"
FT /id="PRO_0000052236"
FT BINDING 349
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000250"
FT HELIX 27..36
FT /evidence="ECO:0007829|PDB:4RM4"
FT STRAND 38..42
FT /evidence="ECO:0007829|PDB:4RM4"
FT TURN 43..46
FT /evidence="ECO:0007829|PDB:4RM4"
FT STRAND 47..50
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 53..61
FT /evidence="ECO:0007829|PDB:4RM4"
FT TURN 63..65
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 80..83
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 88..96
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 97..99
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 102..123
FT /evidence="ECO:0007829|PDB:4RM4"
FT STRAND 127..130
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 131..134
FT /evidence="ECO:0007829|PDB:4RM4"
FT TURN 135..137
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 138..147
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 152..154
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 155..165
FT /evidence="ECO:0007829|PDB:4RM4"
FT STRAND 173..175
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 177..204
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 210..215
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 226..257
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 261..267
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 269..271
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 272..282
FT /evidence="ECO:0007829|PDB:4RM4"
FT STRAND 289..295
FT /evidence="ECO:0007829|PDB:4RM4"
FT STRAND 297..299
FT /evidence="ECO:0007829|PDB:4RM4"
FT STRAND 302..304
FT /evidence="ECO:0007829|PDB:4RM4"
FT STRAND 309..312
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 314..317
FT /evidence="ECO:0007829|PDB:4RM4"
FT TURN 321..323
FT /evidence="ECO:0007829|PDB:4RM4"
FT STRAND 324..326
FT /evidence="ECO:0007829|PDB:4RM4"
FT HELIX 352..369
FT /evidence="ECO:0007829|PDB:4RM4"
FT STRAND 374..380
FT /evidence="ECO:0007829|PDB:4RM4"
FT STRAND 388..395
FT /evidence="ECO:0007829|PDB:4RM4"
SQ SEQUENCE 396 AA; 44991 MW; 9A89CF12613DBCFB CRC64;
MNVLNRRQAL QRALLNGKNK QDAYHPFPWY ESMRKDAPVS FDEENQVWSV FLYDDVKKVV
GDKELFSSCM PQQTSSIGNS IINMDPPKHT KIRSVVNKAF TPRVMKQWEP RIQEITDELI
QKFQGRSEFD LVHDFSYPLP VIVISELLGV PSAHMEQFKA WSDLLVSTPK DKSEEAEKAF
LEERDKCEEE LAAFFAGIIE EKRNKPEQDI ISILVEAEET GEKLSGEELI PFCTLLLVAG
NETTTNLISN AMYSILETPG VYEELRSHPE LMPQAVEEAL RFRAPAPVLR RIAKRDTEIG
GHLIKEGDMV LAFVASANRD EAKFDRPHMF DIRRHPNPHI AFGHGIHFCL GAPLARLEAN
IALTSLISAF PHMECVSITP IENSVIYGLK SFRVKM
