YJJB_KLEAK
ID YJJB_KLEAK Reviewed; 157 AA.
AC A0A0H3FQN0;
DT 03-AUG-2022, integrated into UniProtKB/Swiss-Prot.
DT 16-SEP-2015, sequence version 1.
DT 03-AUG-2022, entry version 29.
DE RecName: Full=Probable succinate transporter subunit YjjB {ECO:0000255|HAMAP-Rule:MF_01191, ECO:0000305};
GN Name=yjjB {ECO:0000255|HAMAP-Rule:MF_01191, ECO:0000303|PubMed:29395959};
GN OrderedLocusNames=EAE_10480 {ECO:0000312|EMBL:AEG97012.1};
OS Klebsiella aerogenes (strain ATCC 13048 / DSM 30053 / CCUG 1429 / JCM 1235
OS / KCTC 2190 / NBRC 13534 / NCIMB 10102 / NCTC 10006 / CDC 819-56)
OS (Enterobacter aerogenes).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=1028307;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 13048 / DSM 30053 / CCUG 1429 / JCM 1235 / KCTC 2190 / NBRC
RC 13534 / NCIMB 10102 / NCTC 10006 / CDC 819-56;
RX PubMed=22493190; DOI=10.1128/jb.00028-12;
RA Shin S.H., Kim S., Kim J.Y., Lee S., Um Y., Oh M.K., Kim Y.R., Lee J.,
RA Yang K.S.;
RT "Complete genome sequence of Enterobacter aerogenes KCTC 2190.";
RL J. Bacteriol. 194:2373-2374(2012).
RN [2]
RP FUNCTION, AND SUBUNIT.
RC STRAIN=AJ110637;
RX PubMed=29395959; DOI=10.1016/j.jbiosc.2017.12.007;
RA Fukui K., Nanatani K., Hara Y., Tokura M., Abe K.;
RT "Identification of EayjjPB encoding a dicarboxylate transporter important
RT for succinate production under aerobic and anaerobic conditions in
RT Enterobacter aerogenes.";
RL J. Biosci. Bioeng. 125:505-512(2018).
CC -!- FUNCTION: Involved in succinate export with YjjP. Both proteins are
CC required for export (PubMed:29395959). Participates in succinate
CC export, but also in the export of other dicarboxylates, such as
CC fumarate and malate (PubMed:29395959). Contributes to succinate
CC production under both aerobic and anaerobic conditions, and increases
CC fumarate and malate production during anaerobic succinate production
CC (PubMed:29395959). {ECO:0000269|PubMed:29395959}.
CC -!- SUBUNIT: The transporter is composed of YjjB and YjjP.
CC {ECO:0000255|HAMAP-Rule:MF_01191, ECO:0000269|PubMed:29395959}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01191, ECO:0000305|PubMed:29395959}; Multi-pass membrane
CC protein {ECO:0000255|HAMAP-Rule:MF_01191}.
CC -!- MISCELLANEOUS: YjjPB constitutes a split-type ThrE family transporter.
CC {ECO:0000303|PubMed:29395959}.
CC -!- SIMILARITY: Belongs to the ThrE exporter (TC 2.A.79) family.
CC {ECO:0000255|HAMAP-Rule:MF_01191, ECO:0000305}.
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DR EMBL; CP002824; AEG97012.1; -; Genomic_DNA.
DR RefSeq; WP_015704312.1; NC_015663.1.
DR RefSeq; YP_004592291.1; NC_015663.1.
DR STRING; 1028307.EAE_10480; -.
DR EnsemblBacteria; AEG97012; AEG97012; EAE_10480.
DR GeneID; 66605635; -.
DR KEGG; eae:EAE_10480; -.
DR PATRIC; fig|1028307.3.peg.2086; -.
DR eggNOG; COG3610; Bacteria.
DR HOGENOM; CLU_117642_1_0_6; -.
DR OMA; IPIEWAT; -.
DR Proteomes; UP000008881; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR HAMAP; MF_01191; YjjB; 1.
DR InterPro; IPR024528; ThrE_2.
DR InterPro; IPR020914; YjjB-like.
DR Pfam; PF12821; ThrE_2; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..157
FT /note="Probable succinate transporter subunit YjjB"
FT /id="PRO_0000456294"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01191"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01191"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01191"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01191"
SQ SEQUENCE 157 AA; 17160 MW; E69119DC38F12358 CRC64;
MGIISYLFDL AQDMALAAIP AVGFAMVFNV PQRALRWCAL LGAIGHGSRM VMMSAGFNIE
WATFLAALLV GSIGIQWSRW YLAHPKIFTV AAVIPMFPGI SAYTAMISAV KISHFGYSEE
MMIMLLSNFL KASSIVGALS IGLSIPGLWL YRKRPRV