YJM0_YEAST
ID YJM0_YEAST Reviewed; 107 AA.
AC P47020;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=Putative uncharacterized protein YJL120W;
GN OrderedLocusNames=YJL120W; ORFNames=J0734;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 96604 / S288c / FY1679;
RX PubMed=8948101;
RX DOI=10.1002/(sici)1097-0061(199611)12:14<1471::aid-yea30>3.0.co;2-4;
RA Cziepluch C., Kordes E., Pujol A., Jauniaux J.-C.;
RT "Sequencing analysis of a 40.2 kb fragment of yeast chromosome X reveals 19
RT open reading frames including URA2 (5' end), TRK1, PBS2, SPT10, GCD14,
RT RPE1, PHO86, NCA3, ASF1, CCT7, GZF3, two tRNA genes, three remnant delta
RT elements and a Ty4 transposon.";
RL Yeast 12:1471-1474(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8641269; DOI=10.1002/j.1460-2075.1996.tb00557.x;
RA Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C.,
RA Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D.,
RA Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J.,
RA Heumann K., Hilger F., Hollenberg C.P., Huang M.-E., Jacq C.,
RA Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E.,
RA Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T.,
RA Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R.,
RA Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N.,
RA To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H.,
RA von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.;
RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.";
RL EMBO J. 15:2031-2049(1996).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP DISRUPTION PHENOTYPE.
RX PubMed=16234568; DOI=10.1093/jnci/dji316;
RA Dilda P.J., Don A.S., Tanabe K.M., Higgins V.J., Allen J.D., Dawes I.W.,
RA Hogg P.J.;
RT "Mechanism of selectivity of an angiogenesis inhibitor from screening a
RT genome-wide set of Saccharomyces cerevisiae deletion strains.";
RL J. Natl. Cancer Inst. 97:1539-1547(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- DISRUPTION PHENOTYPE: Confers sensitivity to the synthetic tripeptide
CC arsenical 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO).
CC {ECO:0000269|PubMed:16234568}.
CC -!- MISCELLANEOUS: Partially overlaps RPE1. Disruption phenotypes caused by
CC deletion of this gene may also be a result of a defect in its
CC overlapping gene. {ECO:0000305}.
CC -!- CAUTION: Product of a dubious gene prediction unlikely to encode a
CC functional protein. Because of that it is not part of the S.cerevisiae
CC S288c complete/reference proteome set. {ECO:0000305|PubMed:24374639}.
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DR EMBL; Z49396; CAA89416.1; -; Genomic_DNA.
DR PIR; S56901; S56901.
DR AlphaFoldDB; P47020; -.
DR DIP; DIP-5293N; -.
DR IntAct; P47020; 1.
DR STRING; 4932.YJL120W; -.
DR PaxDb; P47020; -.
DR EnsemblFungi; YJL120W_mRNA; YJL120W; YJL120W.
DR SGD; S000003656; YJL120W.
DR HOGENOM; CLU_2212009_0_0_1; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 5: Uncertain;
KW Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..107
FT /note="Putative uncharacterized protein YJL120W"
FT /id="PRO_0000203042"
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 107 AA; 12803 MW; 3BD01DD3093646ED CRC64;
MTFATQVGEV RSKDTGSYNW FDHFFLCVYL ALGISKWPSC MKLYRVCFIF LFTGGFFLFW
LSYNRDHERS SSLRIKKVPI HIQKSDYFPS STWIAVLVFS WRHIFCF