ID   YJN2_SCHPO              Reviewed;         449 AA.
AC   Q9P7K3;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Uncharacterized kinase C24B10.02c;
DE            EC=2.7.1.-;
GN   ORFNames=SPCC24B10.02c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
RN   [3]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-420, AND IDENTIFICATION BY
RP   MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the NAD kinase family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU329672; CAB76211.1; -; Genomic_DNA.
DR   PIR; T50409; T50409.
DR   RefSeq; NP_588005.1; NM_001022996.2.
DR   AlphaFoldDB; Q9P7K3; -.
DR   SMR; Q9P7K3; -.
DR   BioGRID; 275821; 6.
DR   STRING; 4896.SPCC24B10.02c.1; -.
DR   iPTMnet; Q9P7K3; -.
DR   MaxQB; Q9P7K3; -.
DR   PaxDb; Q9P7K3; -.
DR   EnsemblFungi; SPCC24B10.02c.1; SPCC24B10.02c.1:pep; SPCC24B10.02c.
DR   GeneID; 2539251; -.
DR   KEGG; spo:SPCC24B10.02c; -.
DR   PomBase; SPCC24B10.02c; -.
DR   VEuPathDB; FungiDB:SPCC24B10.02c; -.
DR   eggNOG; KOG2178; Eukaryota.
DR   HOGENOM; CLU_008831_10_3_1; -.
DR   InParanoid; Q9P7K3; -.
DR   PhylomeDB; Q9P7K3; -.
DR   PRO; PR:Q9P7K3; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0003951; F:NAD+ kinase activity; ISO:PomBase.
DR   GO; GO:0019674; P:NAD metabolic process; ISO:PomBase.
DR   GO; GO:0006741; P:NADP biosynthetic process; IBA:GO_Central.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.200.30; -; 1.
DR   Gene3D; 3.40.50.10330; -; 1.
DR   HAMAP; MF_00361; NAD_kinase; 1.
DR   InterPro; IPR017438; ATP-NAD_kinase_N.
DR   InterPro; IPR017437; ATP-NAD_kinase_PpnK-typ_C.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR   InterPro; IPR002504; NADK.
DR   Pfam; PF01513; NAD_kinase; 1.
DR   SUPFAM; SSF111331; SSF111331; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Kinase; NAD; NADP; Nucleus; Phosphoprotein; Reference proteome;
KW   Transferase.
FT   CHAIN           1..449
FT                   /note="Uncharacterized kinase C24B10.02c"
FT                   /id="PRO_0000316602"
FT   MOD_RES         420
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
SQ   SEQUENCE   449 AA;  50609 MW;  1B4DC3BCA99A75D7 CRC64;
     MATKVEEINK LKKKNLHFRQ CSADSLSNSS MQFDLSGLNT PVGELATSNL PSPAHPPFGE
     LHQESRTSNS SAMHIENVVA SRLMYNEVAN GSFALEPKNI LVVTKPRKHS LVYKTAEITK
     YILTIGTPET KVYVDMRLAR SKRFSAHNIA KEANTDIDRI KYWNPYICLI KPSIFDLAIT
     IGDNSTLLYT SWLFQKIGPP VLSFSDDDVP GFLTHFSLSN YQQHLYQVLT QNVSLRFCSR
     LQCSFHKYDE KTKQYSLAST TYSLDEILIS RGEHPFISNL NVYNNSELMT VVQADGLVVA
     TPTGSTNISA NAGGSLVHPA LNAILVTPVC PHTLSFRPII LPDYNVLNVE IPLDSRSSAF
     FSVDRHESVE MHRGDYLSIV TSHYPFTTIQ NPGYQWTKVL EDKFNWNVRE RQKPFSRKPS
     LSDVKDTSDD KFDITDNSYC REFSADIDG