ID   YJO2_SCHPO              Reviewed;         339 AA.
AC   Q96WV2;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2012, sequence version 2.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Uncharacterized PH domain-containing protein PB16A4.02c;
GN   ORFNames=SPCPB16A4.02c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   REVISION OF GENE MODEL.
RX   PubMed=21511999; DOI=10.1126/science.1203357;
RA   Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA   Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA   Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA   Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA   French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA   Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA   Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA   Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA   Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA   Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT   "Comparative functional genomics of the fission yeasts.";
RL   Science 332:930-936(2011).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Cell
CC       septum {ECO:0000269|PubMed:16823372}. Cell tip
CC       {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329672; CAC39321.2; -; Genomic_DNA.
DR   RefSeq; NP_588026.2; NM_001023017.2.
DR   AlphaFoldDB; Q96WV2; -.
DR   SMR; Q96WV2; -.
DR   BioGRID; 275547; 44.
DR   STRING; 4896.SPCPB16A4.02c.1; -.
DR   iPTMnet; Q96WV2; -.
DR   SwissPalm; Q96WV2; -.
DR   MaxQB; Q96WV2; -.
DR   PaxDb; Q96WV2; -.
DR   PRIDE; Q96WV2; -.
DR   EnsemblFungi; SPCPB16A4.02c.1; SPCPB16A4.02c.1:pep; SPCPB16A4.02c.
DR   GeneID; 2538973; -.
DR   KEGG; spo:SPCPB16A4.02c; -.
DR   PomBase; SPCPB16A4.02c; -.
DR   VEuPathDB; FungiDB:SPCPB16A4.02c; -.
DR   eggNOG; ENOG502QPZK; Eukaryota.
DR   HOGENOM; CLU_826816_0_0_1; -.
DR   InParanoid; Q96WV2; -.
DR   OMA; GQFSYYK; -.
DR   PRO; PR:Q96WV2; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0005938; C:cell cortex; IDA:PomBase.
DR   GO; GO:0032153; C:cell division site; HDA:PomBase.
DR   GO; GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.
DR   GO; GO:0051286; C:cell tip; HDA:PomBase.
DR   GO; GO:0005737; C:cytoplasm; IDA:PomBase.
DR   GO; GO:0005886; C:plasma membrane; ISO:PomBase.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:PomBase.
DR   GO; GO:0140550; F:phosphatidylinositol-4,5-bisphosphate sensor activity; EXP:PomBase.
DR   GO; GO:0005543; F:phospholipid binding; IDA:PomBase.
DR   GO; GO:0031532; P:actin cytoskeleton reorganization; IBA:GO_Central.
DR   GO; GO:1902406; P:mitotic actomyosin contractile ring maintenance; IMP:PomBase.
DR   Gene3D; 2.30.29.30; -; 2.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   Pfam; PF00169; PH; 2.
DR   SMART; SM00233; PH; 2.
DR   PROSITE; PS50003; PH_DOMAIN; 2.
PE   4: Predicted;
KW   Cytoplasm; Reference proteome; Repeat.
FT   CHAIN           1..339
FT                   /note="Uncharacterized PH domain-containing protein
FT                   PB16A4.02c"
FT                   /id="PRO_0000310808"
FT   DOMAIN          25..119
FT                   /note="PH 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00145"
FT   DOMAIN          233..330
FT                   /note="PH 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00145"
FT   REGION          141..170
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   339 AA;  39031 MW;  33E27D0A4182D58E CRC64;
     MDPGVSSHLR TASLDEARRL PELERVLKSG WLIKKGHATS TKKQLWAVLR RDQLSFYKDE
     KEYKTKFIFP TQDISAVAYY KEKSPKTFFL YLNEKIIRLI ATSNEDAEEW VHVLRSTTGY
     RAPFSRHPIS YILANSSSRT ESEPNVQISD TDFDNISTEP RNQTTSPLDL ETGQGDHFCT
     SLYDLIQFGK LRPPGINEEN ANYPFNPQEV NTLNKHRHSA SLQNLYKLLD ENKVLMQGTI
     HWLHGNLHRW SKCWAVVRGY GMTIYNTNRE YKPVKVIPIA DIQDVAEINV PESSHKYFFT
     VITQNKPIEF RVDNEDSLIL WVAALKTSID KANGTFTAC