ID   YJQ5_SCHPO              Reviewed;         301 AA.
AC   Q9USH5;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=PWI domain-containing protein C825.05c;
GN   ORFNames=SPCC825.05c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-86; SER-199 AND SER-291, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00627}.
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DR   EMBL; CU329672; CAB58413.1; -; Genomic_DNA.
DR   PIR; T41626; T41626.
DR   RefSeq; NP_588055.1; NM_001023047.2.
DR   AlphaFoldDB; Q9USH5; -.
DR   SMR; Q9USH5; -.
DR   BioGRID; 276022; 8.
DR   STRING; 4896.SPCC825.05c.1; -.
DR   iPTMnet; Q9USH5; -.
DR   MaxQB; Q9USH5; -.
DR   PaxDb; Q9USH5; -.
DR   PRIDE; Q9USH5; -.
DR   EnsemblFungi; SPCC825.05c.1; SPCC825.05c.1:pep; SPCC825.05c.
DR   GeneID; 2539459; -.
DR   KEGG; spo:SPCC825.05c; -.
DR   PomBase; SPCC825.05c; -.
DR   VEuPathDB; FungiDB:SPCC825.05c; -.
DR   eggNOG; KOG2146; Eukaryota.
DR   HOGENOM; CLU_924890_0_0_1; -.
DR   InParanoid; Q9USH5; -.
DR   PhylomeDB; Q9USH5; -.
DR   PRO; PR:Q9USH5; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0005681; C:spliceosomal complex; ISO:PomBase.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045292; P:mRNA cis splicing, via spliceosome; ISO:PomBase.
DR   GO; GO:0048024; P:regulation of mRNA splicing, via spliceosome; IBA:GO_Central.
DR   InterPro; IPR002483; PWI_dom.
DR   InterPro; IPR036483; PWI_dom_sf.
DR   Pfam; PF01480; PWI; 1.
DR   SMART; SM00311; PWI; 1.
DR   SUPFAM; SSF101233; SSF101233; 1.
DR   PROSITE; PS51025; PWI; 1.
PE   1: Evidence at protein level;
KW   mRNA processing; Nucleus; Phosphoprotein; Reference proteome; RNA-binding.
FT   CHAIN           1..301
FT                   /note="PWI domain-containing protein C825.05c"
FT                   /id="PRO_0000317318"
FT   DOMAIN          26..137
FT                   /note="PWI"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00627"
FT   REGION          145..301
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         86
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   MOD_RES         199
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   MOD_RES         291
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
SQ   SEQUENCE   301 AA;  35631 MW;  C17D330EC3C1B84A CRC64;
     MSGFYKGVAA EQETLFTTAD KKLMRSTKFP ASYDTKVDMK KVNIEVLKPW IATRLNELIG
     FEDEVVINFV YGMLEEAVEA SKTSDSQNES TLDPRKVQLN LTGFLESNAT AFTEELWSLI
     ISASQNQYGI PEKFILEKKE EISKLKDRTE ASKEESKTVT DHSNRRESRR ESTYYDSRER
     NGKRTSRSTL DRKRFHDASD TERNRYGRSP SPHSRFSEKP RGERYDIRSY SRSHKERYED
     RYRPTRRRER HYRTRDDEGF DEFGRSRDGR WRESRTSYRE KHRYDRDALS SESDSGTQKH
     D