ID   YJU2B_DANRE             Reviewed;         390 AA.
AC   Q66I85; Q6TNS9;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Probable splicing factor YJU2B;
DE   AltName: Full=Coiled-coil domain-containing protein 130;
GN   Name=yju2b; Synonyms=ccdc130; ORFNames=zgc:103496;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney marrow;
RX   PubMed=15520368; DOI=10.1073/pnas.0407241101;
RA   Song H.-D., Sun X.-J., Deng M., Zhang G.-W., Zhou Y., Wu X.-Y., Sheng Y.,
RA   Chen Y., Ruan Z., Jiang C.-L., Fan H.-Y., Zon L.I., Kanki J.P., Liu T.X.,
RA   Look A.T., Chen Z.;
RT   "Hematopoietic gene expression profile in zebrafish kidney marrow.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:16240-16245(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in mRNA splicing.
CC       {ECO:0000250|UniProtKB:Q9BW85}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9BW85}.
CC   -!- SIMILARITY: Belongs to the CWC16 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAQ91250.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AY391438; AAQ91250.1; ALT_FRAME; mRNA.
DR   EMBL; BC081482; AAH81482.1; -; mRNA.
DR   RefSeq; NP_991158.2; NM_205595.2.
DR   AlphaFoldDB; Q66I85; -.
DR   SMR; Q66I85; -.
DR   STRING; 7955.ENSDARP00000060887; -.
DR   PaxDb; Q66I85; -.
DR   Ensembl; ENSDART00000060888; ENSDARP00000060887; ENSDARG00000041533.
DR   Ensembl; ENSDART00000169397; ENSDARP00000134561; ENSDARG00000041533.
DR   GeneID; 402887; -.
DR   KEGG; dre:402887; -.
DR   CTD; 81576; -.
DR   ZFIN; ZDB-GENE-040912-36; yju2b.
DR   eggNOG; KOG2990; Eukaryota.
DR   GeneTree; ENSGT00530000063615; -.
DR   HOGENOM; CLU_050402_3_1_1; -.
DR   InParanoid; Q66I85; -.
DR   OrthoDB; 1583452at2759; -.
DR   PhylomeDB; Q66I85; -.
DR   TreeFam; TF313671; -.
DR   PRO; PR:Q66I85; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 22.
DR   Bgee; ENSDARG00000041533; Expressed in tail and 22 other tissues.
DR   ExpressionAtlas; Q66I85; baseline.
DR   GO; GO:0071014; C:post-mRNA release spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0005684; C:U2-type spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR   GO; GO:0008380; P:RNA splicing; IBA:GO_Central.
DR   InterPro; IPR007590; Saf4/Yju2.
DR   PANTHER; PTHR12111; PTHR12111; 1.
DR   Pfam; PF04502; Saf4_Yju2; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..390
FT                   /note="Probable splicing factor YJU2B"
FT                   /id="PRO_0000280740"
FT   REGION          354..390
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        196
FT                   /note="V -> L (in Ref. 1; AAQ91250)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        244
FT                   /note="Q -> L (in Ref. 1; AAQ91250)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        373
FT                   /note="T -> A (in Ref. 1; AAQ91250)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   390 AA;  43768 MW;  F1E894BFBA249234 CRC64;
     MGERKGVNKW YPPDFDPAKH GSINGYYKTH PLRERARKLS QGILIIRFEM PYNIWCDGCK
     NHIGMGVRYN AEKKKVGNYY TTPIYRFRMK CHLCVNYIEM QTDPATCDYV IVSGAQRKEE
     RWDMAENEQI LTTERNEKEK LETDAMYKLD HGGKDKEKLR AAIPSLNELQ EHQSGWKDDF
     QLNSALRRKF RTEKKVIAEE EEKDNAVRLR TGLSIPLVPE REEDKKLASL LTFQSPDSYE
     DKKQWKRQEI SSRSWFNSPS SAAGGAAGSL LQKLGQQGRG AAVAKALSSS TSTLPILVRR
     KSESSKSETN NTMSTILPVD THPAAKDTDA TDLPSIVNNI NVSINTDINS CTTDACKASS
     SSEEENSIDS CATGKSLVAD YSDSDSGSEV