YJY2_YEAST
ID YJY2_YEAST Reviewed; 132 AA.
AC P47087; D6VWI8;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 25-MAY-2022, sequence version 2.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Uncharacterized protein YJR012C {ECO:0000305};
GN OrderedLocusNames=YJR012C {ECO:0000312|SGD:S000003773};
GN ORFNames=J1440, YJR83.25;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8641269; DOI=10.1002/j.1460-2075.1996.tb00557.x;
RA Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C.,
RA Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D.,
RA Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J.,
RA Heumann K., Hilger F., Hollenberg C.P., Huang M.-E., Jacq C.,
RA Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E.,
RA Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T.,
RA Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R.,
RA Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N.,
RA To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H.,
RA von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.;
RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.";
RL EMBO J. 15:2031-2049(1996).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=14690591; DOI=10.1016/s1097-2765(03)00476-3;
RA Hazbun T.R., Malmstroem L., Anderson S., Graczyk B.J., Fox B., Riffle M.,
RA Sundin B.A., Aranda J.D., McDonald W.H., Chiu C.-H., Snydsman B.E.,
RA Bradley P., Muller E.G.D., Fields S., Baker D., Yates J.R. III, Davis T.N.;
RT "Assigning function to yeast proteins by integration of technologies.";
RL Mol. Cell 12:1353-1365(2003).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [6]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-101, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19779198; DOI=10.1126/science.1172867;
RA Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT into evolution.";
RL Science 325:1682-1686(2009).
RN [7]
RP IDENTIFICATION OF PROBABLE INITIATOR METHIONINE.
RX PubMed=29632376; DOI=10.1038/s41588-018-0087-y;
RA Sadhu M.J., Bloom J.S., Day L., Siegel J.J., Kosuri S., Kruglyak L.;
RT "Highly parallel genome variant engineering with CRISPR-Cas9.";
RL Nat. Genet. 50:510-514(2018).
CC -!- SUBUNIT: Copurifies with proteins HOL1, MMP1, PEX7 and PLB1.
CC {ECO:0000269|PubMed:14690591}.
CC -!- MISCELLANEOUS: Present with 538 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAS56226.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CAA60934.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC Sequence=CAA89536.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; X87611; CAA60934.1; ALT_INIT; Genomic_DNA.
DR EMBL; Z49512; CAA89536.1; ALT_INIT; Genomic_DNA.
DR EMBL; AY557900; AAS56226.1; ALT_INIT; Genomic_DNA.
DR EMBL; BK006943; DAA08804.2; -; Genomic_DNA.
DR PIR; S55200; S55200.
DR RefSeq; NP_012546.3; NM_001181670.3.
DR AlphaFoldDB; P47087; -.
DR BioGRID; 300661; 9.
DR DIP; DIP-5042N; -.
DR IntAct; P47087; 5.
DR MINT; P47087; -.
DR STRING; 4932.YJR012C; -.
DR iPTMnet; P47087; -.
DR PaxDb; P47087; -.
DR PRIDE; P47087; -.
DR EnsemblFungi; YJR012C_mRNA; YJR012C; YJR012C.
DR GeneID; 853469; -.
DR KEGG; sce:YJR012C; -.
DR SGD; S000003773; YJR012C.
DR VEuPathDB; FungiDB:YJR012C; -.
DR eggNOG; ENOG502SBU0; Eukaryota.
DR HOGENOM; CLU_1327052_0_0_1; -.
DR InParanoid; P47087; -.
DR OMA; HNESSMA; -.
DR BioCyc; YEAST:G3O-31657-MON; -.
DR PRO; PR:P47087; -.
DR Proteomes; UP000002311; Chromosome X.
DR RNAct; P47087; protein.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..132
FT /note="Uncharacterized protein YJR012C"
FT /id="PRO_0000203083"
FT REGION 36..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 97..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 101
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19779198"
SQ SEQUENCE 132 AA; 14566 MW; 49A2BA49B2F25AC4 CRC64;
MAAGGELSYE ELLDHILNNK PIPNIVEVPN VTLDEGLAST PSLRPRPRPW EGQLQHQSHQ
GSLDKPNISL DIDQESLEGM TSLTRLSECY DIQSKLQIND SDNDNDDNNN DNNKGDGNDD
DNNTVTANPT AR
