YK104_YEAST
ID YK104_YEAST Reviewed; 306 AA.
AC P0CE69; D6VXG5; P36028; P36171; Q53ZY4; Q6Q5L3;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 23-MAR-2010, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Putative uncharacterized protein YKR104W;
GN OrderedLocusNames=YKR104W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8196765; DOI=10.1038/369371a0;
RA Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V.,
RA Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P.,
RA Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L.,
RA Daignan-Fornier B., del Rey F., Dion C., Domdey H., Duesterhoeft A.,
RA Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H.,
RA Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L.,
RA Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M.,
RA Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H.,
RA Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J.,
RA Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H.,
RA Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J.,
RA Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S.,
RA Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F.,
RA Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R.,
RA Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W.,
RA Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M.,
RA Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C.,
RA Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H.,
RA Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L.,
RA van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S.,
RA von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M.,
RA Becker I., Mewes H.-W.;
RT "Complete DNA sequence of yeast chromosome XI.";
RL Nature 369:371-378(1994).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCC family.
CC Conjugate transporter (TC 3.A.1.208) subfamily. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. This is the C-terminal
CC part of the ABC transporter NFT1. S288c has a stop codon in position
CC 1219, which disrupts the gene coding for this protein and produces two
CC ORFs YKR103W and YKR104W. A contiguous sequence for ABC transporter
CC NFT1 can be found in strains Sigma 1278B, EG123 and SK1 (AC P0CE70).
CC {ECO:0000305}.
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DR EMBL; Z28329; CAA82184.1; -; Genomic_DNA.
DR EMBL; AY557949; AAS56275.1; -; Genomic_DNA.
DR EMBL; BK006944; DAA09255.1; -; Genomic_DNA.
DR PIR; S38183; S38183.
DR RefSeq; NP_013030.1; NM_001179894.1.
DR AlphaFoldDB; P0CE69; -.
DR SMR; P0CE69; -.
DR BioGRID; 34235; 95.
DR STRING; 4932.YKR104W; -.
DR iPTMnet; P0CE69; -.
DR PaxDb; P0CE69; -.
DR PRIDE; P0CE69; -.
DR EnsemblFungi; YKR104W_mRNA; YKR104W; YKR104W.
DR GeneID; 853979; -.
DR KEGG; sce:YKR104W; -.
DR SGD; S000001812; YKR104W.
DR VEuPathDB; FungiDB:YKR104W; -.
DR eggNOG; KOG0054; Eukaryota.
DR GeneTree; ENSGT00940000176323; -.
DR HOGENOM; CLU_000604_1_9_1; -.
DR InParanoid; P0CE69; -.
DR OMA; ANQDRIN; -.
DR BioCyc; YEAST:G3O-32066-MON; -.
DR Proteomes; UP000002311; Chromosome XI.
DR RNAct; P0CE69; protein.
DR GO; GO:0000329; C:fungal-type vacuole membrane; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; ISS:SGD.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; ISS:SGD.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 5: Uncertain;
KW ATP-binding; Nucleotide-binding; Reference proteome; Repeat.
FT CHAIN 1..306
FT /note="Putative uncharacterized protein YKR104W"
FT /id="PRO_0000392613"
FT DOMAIN 33..286
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 67..74
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 306 AA; 34652 MW; 43EEE508C07ACDEE CRC64;
MSSVERIKEY TDIPSESNGY ISPPANWPQT GDVELKNLSL RYSPHSSKAL DNVSFKVKAG
TKVGIVGRTG AGKSSIIAAI YRLSDWENGT ITIDNKDIKH IPLERLRNSI SCIPQDPTLF
DGTVRSNLDP FDRYSDVQIY GVLSKVGLIE ECDELCLIFE QEQPNFSSHK LRNRFIDLNT
VVKSGGSNLS QGQRQLLCLA RSMLGARNIM LIDEATASID YISDAKIQKT IRETMKNTTI
LTIAHRLRSV IDYDKILVME MGRVKEYDHP YTLISDRNTI FYRLCRQSGE FENLFELAKV
SFDNKR
