YK21_YEAST
ID YK21_YEAST Reviewed; 250 AA.
AC P36134; D6VXA3;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Uncharacterized protein YKR041W;
GN OrderedLocusNames=YKR041W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8196765; DOI=10.1038/369371a0;
RA Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V.,
RA Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P.,
RA Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L.,
RA Daignan-Fornier B., del Rey F., Dion C., Domdey H., Duesterhoeft A.,
RA Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H.,
RA Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L.,
RA Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M.,
RA Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H.,
RA Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J.,
RA Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H.,
RA Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J.,
RA Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S.,
RA Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F.,
RA Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R.,
RA Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W.,
RA Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M.,
RA Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C.,
RA Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H.,
RA Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L.,
RA van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S.,
RA von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M.,
RA Becker I., Mewes H.-W.;
RT "Complete DNA sequence of yeast chromosome XI.";
RL Nature 369:371-378(1994).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [4]
RP UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-17, AND IDENTIFICATION BY MASS
RP SPECTROMETRY.
RC STRAIN=SUB592;
RX PubMed=12872131; DOI=10.1038/nbt849;
RA Peng J., Schwartz D., Elias J.E., Thoreen C.C., Cheng D., Marsischky G.,
RA Roelofs J., Finley D., Gygi S.P.;
RT "A proteomics approach to understanding protein ubiquitination.";
RL Nat. Biotechnol. 21:921-926(2003).
CC -!- MISCELLANEOUS: Present with 217 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; Z28266; CAA82116.1; -; Genomic_DNA.
DR EMBL; Z28265; CAA82115.1; -; Genomic_DNA.
DR EMBL; BK006944; DAA09193.1; -; Genomic_DNA.
DR PIR; S38113; S38113.
DR RefSeq; NP_012967.1; NM_001179831.1.
DR AlphaFoldDB; P36134; -.
DR BioGRID; 34173; 102.
DR iPTMnet; P36134; -.
DR MaxQB; P36134; -.
DR PaxDb; P36134; -.
DR PRIDE; P36134; -.
DR EnsemblFungi; YKR041W_mRNA; YKR041W; YKR041W.
DR GeneID; 853914; -.
DR KEGG; sce:YKR041W; -.
DR SGD; S000001749; YKR041W.
DR VEuPathDB; FungiDB:YKR041W; -.
DR eggNOG; ENOG502S83T; Eukaryota.
DR HOGENOM; CLU_077477_0_0_1; -.
DR InParanoid; P36134; -.
DR OMA; ATSKDNI; -.
DR BioCyc; YEAST:G3O-32012-MON; -.
DR PRO; PR:P36134; -.
DR Proteomes; UP000002311; Chromosome XI.
DR RNAct; P36134; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR GO; GO:0072686; C:mitotic spindle; IDA:SGD.
DR GO; GO:0005634; C:nucleus; IDA:SGD.
PE 1: Evidence at protein level;
KW Isopeptide bond; Reference proteome; Ubl conjugation.
FT CHAIN 1..250
FT /note="Uncharacterized protein YKR041W"
FT /id="PRO_0000203210"
FT REGION 30..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..50
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CROSSLNK 17
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in ubiquitin)"
FT /evidence="ECO:0000269|PubMed:12872131"
SQ SEQUENCE 250 AA; 29208 MW; 1B450E0F093DD123 CRC64;
MSDDDYMNSD DDNDAEKRYV RPIFVRKRRR EEDYVATSKD NIHHHPCDWS AKPSQRQNEN
EQKSTIRLVP VAMNTPKCQE KKKKRKGVGT TSHEATLFEY GESIAGYKCV TTESERDRLK
RSHESESSSE SEVDVFAFDQ AKGISSKVEA EERYARAVRQ YWRMTKDEPA TLPLPGTPTL
AAVSLDMIDD KSVEQFYTMS SALMDANRLD LIRRDRIRWH PDKHRYHKSK VTKLFQAING
LWEQEKTEKR
