ID   YK27_CAEEL              Reviewed;         432 AA.
AC   O16686;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Uncharacterized protein K07E8.7;
GN   ORFNames=K07E8.7;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SIMILARITY: Belongs to the pseudouridine synthase RluA family.
CC       {ECO:0000305}.
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DR   EMBL; FO081602; CCD72759.1; -; Genomic_DNA.
DR   PIR; T32044; T32044.
DR   RefSeq; NP_493778.1; NM_061377.4.
DR   AlphaFoldDB; O16686; -.
DR   SMR; O16686; -.
DR   STRING; 6239.K07E8.7; -.
DR   EPD; O16686; -.
DR   PaxDb; O16686; -.
DR   PeptideAtlas; O16686; -.
DR   EnsemblMetazoa; K07E8.7a.1; K07E8.7a.1; WBGene00019498.
DR   GeneID; 173456; -.
DR   UCSC; K07E8.7; c. elegans.
DR   CTD; 173456; -.
DR   WormBase; K07E8.7a; CE11898; WBGene00019498; -.
DR   eggNOG; KOG1919; Eukaryota.
DR   GeneTree; ENSGT00420000029802; -.
DR   HOGENOM; CLU_016902_12_5_1; -.
DR   InParanoid; O16686; -.
DR   OMA; RYRYNTI; -.
DR   OrthoDB; 821308at2759; -.
DR   PhylomeDB; O16686; -.
DR   PRO; PR:O16686; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00019498; Expressed in germ line (C elegans) and 4 other tissues.
DR   ExpressionAtlas; O16686; baseline.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000455; P:enzyme-directed rRNA pseudouridine synthesis; IBA:GO_Central.
DR   CDD; cd00165; S4; 1.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR   InterPro; IPR006225; PsdUridine_synth_RluC/D.
DR   InterPro; IPR006224; PsdUridine_synth_RluC/D_CS.
DR   InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   Pfam; PF00849; PseudoU_synth_2; 1.
DR   SUPFAM; SSF55120; SSF55120; 1.
DR   TIGRFAMs; TIGR00005; rluA_subfam; 1.
DR   PROSITE; PS01129; PSI_RLU; 1.
DR   PROSITE; PS50889; S4; 1.
PE   3: Inferred from homology;
KW   Reference proteome; RNA-binding.
FT   CHAIN           1..432
FT                   /note="Uncharacterized protein K07E8.7"
FT                   /id="PRO_0000162758"
FT   DOMAIN          85..148
FT                   /note="S4 RNA-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00182"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..42
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        199
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   432 AA;  50011 MW;  ABC908A4BAA84734 CRC64;
     MSDTTDVPEN QKSPKPSGKA DKRKIEEKPE NSSLKRKKFE DPNKKVDPLE ELPMKVPFKI
     VDGVRHLAPY WACYRTRTKG RWIGRKMVEV FSGEFLSTNR NYAKIACKMG RIYVNGEQMT
     DVDYVMRNGD RVEHWAHRHE HPIRDLPIRV ISETDDLFVV EKPPSLPVHT CGQYAIHTVL
     GQLRVNEGRT GLRVLHRLDR ATSGVLLFAK NYETDLEFKT TLKQGEWSKE YICKVDGVFP
     DEEQVCEQPI GPLVISMGIQ CVRPDGKDAK SRFRKLWSDG TQSVVQVHIE TGRTHQIRVH
     SQFLGHPIAG DQIYNSAVWG PTKGKNADYQ KSFDELCEDV RNTHKCENWH EKPNPEFEQR
     MEHLAADTTP ITPEAPSLTL EQRPEFDEIC QKCNVESKKV PENHFQLYLH CLKYETKKWS
     FKTEMPDWAV QK