YK50_YEAST
ID YK50_YEAST Reviewed; 352 AA.
AC P36151; D6VXD1;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 03-AUG-2022, entry version 148.
DE RecName: Full=Uncharacterized protein YKR070W;
GN OrderedLocusNames=YKR070W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8196765; DOI=10.1038/369371a0;
RA Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V.,
RA Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P.,
RA Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L.,
RA Daignan-Fornier B., del Rey F., Dion C., Domdey H., Duesterhoeft A.,
RA Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H.,
RA Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L.,
RA Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M.,
RA Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H.,
RA Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J.,
RA Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H.,
RA Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J.,
RA Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S.,
RA Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F.,
RA Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R.,
RA Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W.,
RA Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M.,
RA Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C.,
RA Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H.,
RA Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L.,
RA van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S.,
RA von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M.,
RA Becker I., Mewes H.-W.;
RT "Complete DNA sequence of yeast chromosome XI.";
RL Nature 369:371-378(1994).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS
RP SPECTROMETRY.
RX PubMed=16823961; DOI=10.1021/pr050477f;
RA Reinders J., Zahedi R.P., Pfanner N., Meisinger C., Sickmann A.;
RT "Toward the complete yeast mitochondrial proteome: multidimensional
RT separation techniques for mitochondrial proteomics.";
RL J. Proteome Res. 5:1543-1554(2006).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:16823961}.
CC -!- MISCELLANEOUS: Present with 3870 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; Z28295; CAA82149.1; -; Genomic_DNA.
DR EMBL; BK006944; DAA09221.1; -; Genomic_DNA.
DR PIR; S38147; S38147.
DR RefSeq; NP_012996.1; NM_001179860.1.
DR PDB; 3KC2; X-ray; 1.55 A; A/B=1-352.
DR PDB; 3RF6; X-ray; 1.70 A; A/B=1-352.
DR PDBsum; 3KC2; -.
DR PDBsum; 3RF6; -.
DR AlphaFoldDB; P36151; -.
DR SMR; P36151; -.
DR BioGRID; 34201; 36.
DR DIP; DIP-4076N; -.
DR MINT; P36151; -.
DR STRING; 4932.YKR070W; -.
DR iPTMnet; P36151; -.
DR MaxQB; P36151; -.
DR PaxDb; P36151; -.
DR PRIDE; P36151; -.
DR EnsemblFungi; YKR070W_mRNA; YKR070W; YKR070W.
DR GeneID; 853944; -.
DR KEGG; sce:YKR070W; -.
DR SGD; S000001778; YKR070W.
DR VEuPathDB; FungiDB:YKR070W; -.
DR eggNOG; KOG1618; Eukaryota.
DR GeneTree; ENSGT00940000175279; -.
DR HOGENOM; CLU_030880_1_0_1; -.
DR InParanoid; P36151; -.
DR OMA; CTSILVC; -.
DR BioCyc; YEAST:G3O-32036-MON; -.
DR EvolutionaryTrace; P36151; -.
DR PRO; PR:P36151; -.
DR Proteomes; UP000002311; Chromosome XI.
DR RNAct; P36151; protein.
DR GO; GO:0005739; C:mitochondrion; HDA:SGD.
DR GO; GO:0046474; P:glycerophospholipid biosynthetic process; IBA:GO_Central.
DR Gene3D; 3.40.50.1000; -; 2.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR006357; HAD-SF_hydro_IIA.
DR InterPro; IPR006353; HAD-SF_hydro_IIA_CECR5.
DR InterPro; IPR023214; HAD_sf.
DR Pfam; PF13344; Hydrolase_6; 1.
DR SUPFAM; SSF56784; SSF56784; 1.
DR TIGRFAMs; TIGR01456; CECR5; 1.
DR TIGRFAMs; TIGR01460; HAD-SF-IIA; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Mitochondrion; Reference proteome.
FT CHAIN 1..352
FT /note="Uncharacterized protein YKR070W"
FT /id="PRO_0000203218"
FT STRAND 14..18
FT /evidence="ECO:0007829|PDB:3KC2"
FT TURN 21..23
FT /evidence="ECO:0007829|PDB:3KC2"
FT STRAND 24..26
FT /evidence="ECO:0007829|PDB:3KC2"
FT HELIX 34..43
FT /evidence="ECO:0007829|PDB:3KC2"
FT STRAND 48..51
FT /evidence="ECO:0007829|PDB:3KC2"
FT HELIX 59..70
FT /evidence="ECO:0007829|PDB:3KC2"
FT HELIX 76..78
FT /evidence="ECO:0007829|PDB:3KC2"
FT HELIX 84..89
FT /evidence="ECO:0007829|PDB:3KC2"
FT TURN 90..92
FT /evidence="ECO:0007829|PDB:3KC2"
FT STRAND 94..101
FT /evidence="ECO:0007829|PDB:3KC2"
FT HELIX 104..111
FT /evidence="ECO:0007829|PDB:3KC2"
FT STRAND 114..118
FT /evidence="ECO:0007829|PDB:3KC2"
FT HELIX 119..125
FT /evidence="ECO:0007829|PDB:3KC2"
FT HELIX 127..129
FT /evidence="ECO:0007829|PDB:3KC2"
FT HELIX 137..143
FT /evidence="ECO:0007829|PDB:3KC2"
FT TURN 148..152
FT /evidence="ECO:0007829|PDB:3KC2"
FT STRAND 157..160
FT /evidence="ECO:0007829|PDB:3KC2"
FT HELIX 167..178
FT /evidence="ECO:0007829|PDB:3KC2"
FT STRAND 200..203
FT /evidence="ECO:0007829|PDB:3KC2"
FT STRAND 207..209
FT /evidence="ECO:0007829|PDB:3KC2"
FT STRAND 212..215
FT /evidence="ECO:0007829|PDB:3KC2"
FT HELIX 220..235
FT /evidence="ECO:0007829|PDB:3KC2"
FT HELIX 249..267
FT /evidence="ECO:0007829|PDB:3KC2"
FT STRAND 268..270
FT /evidence="ECO:0007829|PDB:3RF6"
FT TURN 285..289
FT /evidence="ECO:0007829|PDB:3KC2"
FT STRAND 290..298
FT /evidence="ECO:0007829|PDB:3KC2"
FT TURN 300..302
FT /evidence="ECO:0007829|PDB:3KC2"
FT HELIX 303..310
FT /evidence="ECO:0007829|PDB:3KC2"
FT STRAND 313..316
FT /evidence="ECO:0007829|PDB:3KC2"
FT STRAND 318..321
FT /evidence="ECO:0007829|PDB:3KC2"
FT STRAND 334..336
FT /evidence="ECO:0007829|PDB:3KC2"
FT HELIX 340..351
FT /evidence="ECO:0007829|PDB:3KC2"
SQ SEQUENCE 352 AA; 39406 MW; 92A8EE00D9169DAA CRC64;
MIGKRFFQTT SKKIAFAFDI DGVLFRGKKP IAGASDALKL LNRNKIPYIL LTNGGGFSER
ARTEFISSKL DVDVSPLQII QSHTPYKSLV NKYSRILAVG TPSVRGVAEG YGFQDVVHQT
DIVRYNRDIA PFSGLSDEQV MEYSRDIPDL TTKKFDAVLV FNDPHDWAAD IQIISDAINS
ENGMLNTLRN EKSGKPSIPI YFSNQDLLWA NPYKLNRFGQ GAFRLLVRRL YLELNGEPLQ
DYTLGKPTKL TYDFAHHVLI DWEKRLSGKI GQSVKQKLPL LGTKPSTSPF HAVFMVGDNP
ASDIIGAQNY GWNSCLVKTG VYNEGDDLKE CKPTLIVNDV FDAVTKTLEK YA
