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YK58_YEAST
ID   YK58_YEAST              Reviewed;         585 AA.
AC   P36158; D6VXD8;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=Uncharacterized protein YKR078W;
GN   OrderedLocusNames=YKR078W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8196765; DOI=10.1038/369371a0;
RA   Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V.,
RA   Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P.,
RA   Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L.,
RA   Daignan-Fornier B., del Rey F., Dion C., Domdey H., Duesterhoeft A.,
RA   Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H.,
RA   Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L.,
RA   Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M.,
RA   Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H.,
RA   Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J.,
RA   Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H.,
RA   Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J.,
RA   Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S.,
RA   Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F.,
RA   Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R.,
RA   Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W.,
RA   Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M.,
RA   Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C.,
RA   Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H.,
RA   Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L.,
RA   van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S.,
RA   von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M.,
RA   Becker I., Mewes H.-W.;
RT   "Complete DNA sequence of yeast chromosome XI.";
RL   Nature 369:371-378(1994).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA   O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
CC   -!- MISCELLANEOUS: Present with 1270 molecules/cell in log phase SD medium.
CC       {ECO:0000269|PubMed:14562106}.
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DR   EMBL; Z28303; CAA82157.1; -; Genomic_DNA.
DR   EMBL; BK006944; DAA09228.1; -; Genomic_DNA.
DR   PIR; S38155; S38155.
DR   RefSeq; NP_013004.3; NM_001179868.3.
DR   AlphaFoldDB; P36158; -.
DR   SMR; P36158; -.
DR   BioGRID; 34209; 46.
DR   DIP; DIP-7328N; -.
DR   MINT; P36158; -.
DR   STRING; 4932.YKR078W; -.
DR   iPTMnet; P36158; -.
DR   MaxQB; P36158; -.
DR   PaxDb; P36158; -.
DR   PRIDE; P36158; -.
DR   EnsemblFungi; YKR078W_mRNA; YKR078W; YKR078W.
DR   GeneID; 853953; -.
DR   KEGG; sce:YKR078W; -.
DR   SGD; S000001786; YKR078W.
DR   VEuPathDB; FungiDB:YKR078W; -.
DR   eggNOG; KOG2273; Eukaryota.
DR   HOGENOM; CLU_444920_0_0_1; -.
DR   InParanoid; P36158; -.
DR   OMA; INEFTEC; -.
DR   BioCyc; YEAST:G3O-32042-MON; -.
DR   PRO; PR:P36158; -.
DR   Proteomes; UP000002311; Chromosome XI.
DR   RNAct; P36158; protein.
DR   GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0005768; C:endosome; IBA:GO_Central.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IBA:GO_Central.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.
DR   GO; GO:0045053; P:protein retention in Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IBA:GO_Central.
DR   Gene3D; 1.20.1270.60; -; 1.
DR   Gene3D; 3.30.1520.10; -; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR028648; Vps5-like.
DR   InterPro; IPR015404; Vps5_C.
DR   PANTHER; PTHR10555:SF170; PTHR10555:SF170; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF09325; Vps5; 1.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF64268; SSF64268; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..585
FT                   /note="Uncharacterized protein YKR078W"
FT                   /id="PRO_0000203224"
FT   REGION          27..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   585 AA;  68281 MW;  45677C7B39E1235E CRC64;
     MENDKASHAS PSIGVNEFVV QGEISIDDSE RSVKSVSVSI SDDEDSKTDV QDNMATPSTR
     SKFQTDLAID NRLLEKDPKY KKLFTEKRRR RRPESCINLM TKGKGTGQKD NINDQIFSLR
     ILPGSDLNSL KDSLWIIKIS TQPDVEKTIA RAFSDFYWLY HQLQNNHWGK TIPPPTRSNI
     LVEKDEFAIN HLFMIRNNEK YDPIFNFKPE YIISLQLMAM IKHIFNDKVL RLDSNFIDFI
     SWDDDLPESL QIVVDDSTFT GDKILMTSSQ FRELKEFHKQ SKKVESITNS HASLIPVTEL
     TEIYISPTKL FSRKDYQRLF QPQSTDNTFN NNDPLIQEWI PKSKTLFTSL SFGSSAPTYQ
     EASTEIQACH DWVSISKEQW KQLLYHVLQY IVDEAVKVNS VINEFTECLK QISLDEVIRA
     NSELFLKFSK LNESFLKKFK GASRQDILKL IILFDENVRF CESFESILNQ RLKLGKILSI
     IEVDLDKKKN FLDKLSPGNN NSNNEDLKIR TAEDEYRIVL KRYNRVKQSW EKIMEDILNE
     RKEFEKREAA EVNSCLKSIR DLNMDEKKHY LQLWQDFVPD EHISQ
 
 
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