YK58_YEAST
ID YK58_YEAST Reviewed; 585 AA.
AC P36158; D6VXD8;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Uncharacterized protein YKR078W;
GN OrderedLocusNames=YKR078W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8196765; DOI=10.1038/369371a0;
RA Dujon B., Alexandraki D., Andre B., Ansorge W., Baladron V.,
RA Ballesta J.P.G., Banrevi A., Bolle P.-A., Bolotin-Fukuhara M., Bossier P.,
RA Bou G., Boyer J., Buitrago M.J., Cheret G., Colleaux L.,
RA Daignan-Fornier B., del Rey F., Dion C., Domdey H., Duesterhoeft A.,
RA Duesterhus S., Entian K.-D., Erfle H., Esteban P.F., Feldmann H.,
RA Fernandes L., Fobo G.M., Fritz C., Fukuhara H., Gabel C., Gaillon L.,
RA Garcia-Cantalejo J.M., Garcia-Ramirez J.J., Gent M.E., Ghazvini M.,
RA Goffeau A., Gonzalez A., Grothues D., Guerreiro P., Hegemann J.H.,
RA Hewitt N., Hilger F., Hollenberg C.P., Horaitis O., Indge K.J.,
RA Jacquier A., James C.M., Jauniaux J.-C., Jimenez A., Keuchel H.,
RA Kirchrath L., Kleine K., Koetter P., Legrain P., Liebl S., Louis E.J.,
RA Maia e Silva A., Marck C., Monnier A.-L., Moestl D., Mueller S.,
RA Obermaier B., Oliver S.G., Pallier C., Pascolo S., Pfeiffer F.,
RA Philippsen P., Planta R.J., Pohl F.M., Pohl T.M., Poehlmann R.,
RA Portetelle D., Purnelle B., Puzos V., Ramezani Rad M., Rasmussen S.W.,
RA Remacha M.A., Revuelta J.L., Richard G.-F., Rieger M.,
RA Rodrigues-Pousada C., Rose M., Rupp T., Santos M.A., Schwager C.,
RA Sensen C., Skala J., Soares H., Sor F., Stegemann J., Tettelin H.,
RA Thierry A., Tzermia M., Urrestarazu L.A., van Dyck L.,
RA van Vliet-Reedijk J.C., Valens M., Vandenbol M., Vilela C., Vissers S.,
RA von Wettstein D., Voss H., Wiemann S., Xu G., Zimmermann J., Haasemann M.,
RA Becker I., Mewes H.-W.;
RT "Complete DNA sequence of yeast chromosome XI.";
RL Nature 369:371-378(1994).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- MISCELLANEOUS: Present with 1270 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; Z28303; CAA82157.1; -; Genomic_DNA.
DR EMBL; BK006944; DAA09228.1; -; Genomic_DNA.
DR PIR; S38155; S38155.
DR RefSeq; NP_013004.3; NM_001179868.3.
DR AlphaFoldDB; P36158; -.
DR SMR; P36158; -.
DR BioGRID; 34209; 46.
DR DIP; DIP-7328N; -.
DR MINT; P36158; -.
DR STRING; 4932.YKR078W; -.
DR iPTMnet; P36158; -.
DR MaxQB; P36158; -.
DR PaxDb; P36158; -.
DR PRIDE; P36158; -.
DR EnsemblFungi; YKR078W_mRNA; YKR078W; YKR078W.
DR GeneID; 853953; -.
DR KEGG; sce:YKR078W; -.
DR SGD; S000001786; YKR078W.
DR VEuPathDB; FungiDB:YKR078W; -.
DR eggNOG; KOG2273; Eukaryota.
DR HOGENOM; CLU_444920_0_0_1; -.
DR InParanoid; P36158; -.
DR OMA; INEFTEC; -.
DR BioCyc; YEAST:G3O-32042-MON; -.
DR PRO; PR:P36158; -.
DR Proteomes; UP000002311; Chromosome XI.
DR RNAct; P36158; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005768; C:endosome; IBA:GO_Central.
DR GO; GO:0035091; F:phosphatidylinositol binding; IBA:GO_Central.
DR GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IDA:SGD.
DR GO; GO:0045053; P:protein retention in Golgi apparatus; IBA:GO_Central.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IBA:GO_Central.
DR Gene3D; 1.20.1270.60; -; 1.
DR Gene3D; 3.30.1520.10; -; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR028648; Vps5-like.
DR InterPro; IPR015404; Vps5_C.
DR PANTHER; PTHR10555:SF170; PTHR10555:SF170; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF09325; Vps5; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; SSF64268; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..585
FT /note="Uncharacterized protein YKR078W"
FT /id="PRO_0000203224"
FT REGION 27..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 585 AA; 68281 MW; 45677C7B39E1235E CRC64;
MENDKASHAS PSIGVNEFVV QGEISIDDSE RSVKSVSVSI SDDEDSKTDV QDNMATPSTR
SKFQTDLAID NRLLEKDPKY KKLFTEKRRR RRPESCINLM TKGKGTGQKD NINDQIFSLR
ILPGSDLNSL KDSLWIIKIS TQPDVEKTIA RAFSDFYWLY HQLQNNHWGK TIPPPTRSNI
LVEKDEFAIN HLFMIRNNEK YDPIFNFKPE YIISLQLMAM IKHIFNDKVL RLDSNFIDFI
SWDDDLPESL QIVVDDSTFT GDKILMTSSQ FRELKEFHKQ SKKVESITNS HASLIPVTEL
TEIYISPTKL FSRKDYQRLF QPQSTDNTFN NNDPLIQEWI PKSKTLFTSL SFGSSAPTYQ
EASTEIQACH DWVSISKEQW KQLLYHVLQY IVDEAVKVNS VINEFTECLK QISLDEVIRA
NSELFLKFSK LNESFLKKFK GASRQDILKL IILFDENVRF CESFESILNQ RLKLGKILSI
IEVDLDKKKN FLDKLSPGNN NSNNEDLKIR TAEDEYRIVL KRYNRVKQSW EKIMEDILNE
RKEFEKREAA EVNSCLKSIR DLNMDEKKHY LQLWQDFVPD EHISQ