ID   YK68_SCHPO              Reviewed;         579 AA.
AC   Q9US10;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Uncharacterized membrane protein C6F6.13c;
GN   ORFNames=SPAC607.08c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       membrane {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the TMCO4 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU329670; CAB63795.1; -; Genomic_DNA.
DR   PIR; T50228; T50228.
DR   RefSeq; NP_593597.1; NM_001019028.1.
DR   AlphaFoldDB; Q9US10; -.
DR   SMR; Q9US10; -.
DR   BioGRID; 279582; 1.
DR   STRING; 4896.SPAC607.08c.1; -.
DR   ESTHER; schpo-yk68; Duf_726.
DR   SwissPalm; Q9US10; -.
DR   MaxQB; Q9US10; -.
DR   PaxDb; Q9US10; -.
DR   EnsemblFungi; SPAC607.08c.1; SPAC607.08c.1:pep; SPAC607.08c.
DR   GeneID; 2543150; -.
DR   KEGG; spo:SPAC607.08c; -.
DR   PomBase; SPAC607.08c; -.
DR   VEuPathDB; FungiDB:SPAC607.08c; -.
DR   eggNOG; KOG2385; Eukaryota.
DR   HOGENOM; CLU_007407_0_1_1; -.
DR   InParanoid; Q9US10; -.
DR   OMA; EHISWSW; -.
DR   PhylomeDB; Q9US10; -.
DR   PRO; PR:Q9US10; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0016298; F:lipase activity; TAS:PomBase.
DR   GO; GO:0016192; P:vesicle-mediated transport; TAS:PomBase.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR007941; DUF726.
DR   PANTHER; PTHR17920; PTHR17920; 1.
DR   Pfam; PF05277; DUF726; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Membrane; Nucleus; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..579
FT                   /note="Uncharacterized membrane protein C6F6.13c"
FT                   /id="PRO_0000340088"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        196..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   579 AA;  63631 MW;  162E03BA55982ACF CRC64;
     MAEQKIISLF DDDACTRYTI LIASTIGEMR EKKESIIDNT DPEIVKYLSQ LLDVFRENFD
     TWAMAVVNRT GCALDPSTPK DQVEVKKFRQ FSETEKSECF IKCLLLLILS LGNYSPYSRN
     LLYSIAEKLG LSSIVVYKAE LITSSMLLDT FQTMESNQEM YELSGTRKMR RRIAMGLAGL
     AGGALIGLTG GLAAPFVAAG LGTLFAGLGL GTMIGATYLG TLITSAPMIT ALFGGFGAKM
     SMQQMGDVSK GLTDFEFIPL SVQSHLPVTI GISGWLGDYN EVDAAWKSLT VGDKSYYWGD
     IYALKFEVEA LVDLGKSLSR ILFSAGLGWV KGEVISRTIL APLAAALWPL SLLKVGNILG
     NSWRIAFNLS IKAGEALANA LCVRAQGMRP VTLIGFSLGA RTILECLLHL ADRGETNLVE
     NVIVMGAPMP TDAKLWLKMR CVVAGRFVNV YSASDYVLQL VYRVNSAQST AAGLGPVSLD
     SNTLENVDVG DLVEGHLQYR WLVAKILKER LGYDNISDAE IQSLAVQEEK YESKQRTYYS
     QKEQEEEIEQ EVLFDASSDT ELAIQKKEDE VNEVRENKK