YKFC_ECOLI
ID YKFC_ECOLI Reviewed; 381 AA.
AC Q47688; A0A385XJA9; P77710;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 07-NOV-2018, sequence version 3.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Protein YkfC;
GN Name=ykfC; OrderedLocusNames=b0258, JW5813;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RA Takemoto K., Mori H., Murayama N., Kataoka K., Yano M., Itoh T.,
RA Yamamoto Y., Inokuchi H., Miki T., Hatada E., Fukuda R., Ichihara S.,
RA Mizuno T., Makino K., Nakata A., Yura T., Sampei G., Mizobuchi K.;
RT "Systematic sequencing of the Escherichia coli genome: analysis of the 4.0
RT - 6.0 min (189,987 - 281,416bp) region.";
RL Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RA Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT "Sequence of minutes 4-25 of Escherichia coli.";
RL Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- MISCELLANEOUS: Encoded by the CP4-6 prophage. {ECO:0000305}.
CC -!- MISCELLANEOUS: A short reverse transcriptase-like protein missing about
CC 140 C-terminal residues compared to orthologs. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the bacterial reverse transcriptase family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB08678.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; U70214; AAB08678.1; ALT_INIT; Genomic_DNA.
DR EMBL; U00096; AYC08169.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA77927.2; -; Genomic_DNA.
DR PIR; B64751; B64751.
DR AlphaFoldDB; Q47688; -.
DR SMR; Q47688; -.
DR BioGRID; 4262795; 116.
DR STRING; 316407.85674402; -.
DR PRIDE; Q47688; -.
DR EnsemblBacteria; AYC08169; AYC08169; b0258.
DR EnsemblBacteria; BAA77927; BAA77927; BAA77927.
DR KEGG; ecj:JW5813; -.
DR EchoBASE; EB3125; -.
DR eggNOG; COG3344; Bacteria.
DR HOGENOM; CLU_013584_4_0_6; -.
DR InParanoid; Q47688; -.
DR PhylomeDB; Q47688; -.
DR BioCyc; EcoCyc:G6133-MON; -.
DR PRO; PR:Q47688; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR000477; RT_dom.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; SSF56672; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 3: Inferred from homology;
KW Magnesium; Metal-binding; Reference proteome.
FT CHAIN 1..381
FT /note="Protein YkfC"
FT /id="PRO_0000168548"
FT DOMAIN 72..337
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00405"
FT BINDING 166
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00405"
FT BINDING 284
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00405"
FT BINDING 285
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00405"
SQ SEQUENCE 381 AA; 43739 MW; 1AE71F6B242CC91F CRC64;
MIISEMQRKL ATWAATDPSL RIQRLLRLIT QPEWLAEAAR ITLSSKGAHT PGVDGVNKTM
LQARLAVELQ ILRDELLSGH YQPLPARRVY IPKSNGKLRP LGIPALRDRI VQRAMLMAME
PIWESDFHTL SYGFRPERSV HHAIRTVKLQ LTDCGETRGR WVIEGDLSSY FDTVHHRLLM
KAVRRRISDA RFMTLLWKTI KAGHIDVGLF RAASEGVPQG GVISPLLSNI MLNEFDQYLH
ERYLSGKARK DRWYWNNSIQ RGRSTAVREN WQWKPAVAYC RYADDFVLIV KGTKAQVEAI
REECRGVLEG SLKLRLNMDK TKIPHVNDGF IFLGHRLIRK RSRYGEMRVV STIPQEKARN
FAASLTALLW KVRISGEILL G
