ID   YKGA_ECOLI              Reviewed;         239 AA.
AC   P77601; Q2MCC1;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 140.
DE   RecName: Full=Putative HTH-type transcriptional regulator YkgA;
GN   Name=ykgA; OrderedLocusNames=b0300, JW5037;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RA   Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA   Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA   Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT   "Sequence of minutes 4-25 of Escherichia coli.";
RL   Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAE76085.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; U73857; AAB18028.1; -; Genomic_DNA.
DR   EMBL; U00096; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP009048; BAE76085.1; ALT_INIT; Genomic_DNA.
DR   PIR; D64756; D64756.
DR   AlphaFoldDB; P77601; -.
DR   SMR; P77601; -.
DR   BioGRID; 4259797; 12.
DR   STRING; 316407.85674445; -.
DR   PRIDE; P77601; -.
DR   EnsemblBacteria; BAE76085; BAE76085; BAE76085.
DR   KEGG; ecj:JW5037; -.
DR   EchoBASE; EB3162; -.
DR   eggNOG; COG2207; Bacteria.
DR   eggNOG; COG3708; Bacteria.
DR   HOGENOM; CLU_000445_81_1_6; -.
DR   InParanoid; P77601; -.
DR   PhylomeDB; P77601; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR011256; Reg_factor_effector_dom_sf.
DR   InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR   Pfam; PF12833; HTH_18; 1.
DR   PRINTS; PR00032; HTHARAC.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   SUPFAM; SSF55136; SSF55136; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   5: Uncertain;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..239
FT                   /note="Putative HTH-type transcriptional regulator YkgA"
FT                   /id="PRO_0000194612"
FT   DOMAIN          19..117
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        36..57
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        84..107
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ   SEQUENCE   239 AA;  28475 MW;  12C035E165A38522 CRC64;
     MRYDKELTEN EMIRQKILQQ LLEWIECNLE HPISIEDIAQ KSGYSRRNIQ LLFRNFMHVP
     LGEYIRKRRL CRAAILVRLT AKSMLDIALS LHFDSQQSFS REFKKLFGCS PREYRHRDYW
     DLANIFPSFL IRQQQKTECR LINFPETPIF GNSFKYDIEV SNKSPDEEVK LRRHHLARCM
     KNFKTDIYFV STFEPSTKSV DLLTVETFAG TVCEYADMPK EWTTTRGLYD PTHVIWTQA