ID   YKGC_SCHPO              Reviewed;         376 AA.
AC   Q9UT29;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Uncharacterized protein C8F11.08c;
GN   ORFNames=SPAC8F11.08c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   FUNCTION.
RX   PubMed=16169489; DOI=10.1016/j.cub.2005.07.059;
RA   Gregan J., Rabitsch P.K., Sakem B., Csutak O., Latypov V., Lehmann E.,
RA   Kohli J., Nasmyth K.;
RT   "Novel genes required for meiotic chromosome segregation are identified by
RT   a high-throughput knockout screen in fission yeast.";
RL   Curr. Biol. 15:1663-1669(2005).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Has a role in meiotic chromosome segregation.
CC       {ECO:0000269|PubMed:16169489}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC       Multi-pass membrane protein {ECO:0000305}.
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DR   EMBL; CU329670; CAB52169.1; -; Genomic_DNA.
DR   PIR; T39183; T39183.
DR   RefSeq; NP_593957.1; NM_001019384.2.
DR   AlphaFoldDB; Q9UT29; -.
DR   SMR; Q9UT29; -.
DR   STRING; 4896.SPAC8F11.08c.1; -.
DR   MaxQB; Q9UT29; -.
DR   PaxDb; Q9UT29; -.
DR   EnsemblFungi; SPAC8F11.08c.1; SPAC8F11.08c.1:pep; SPAC8F11.08c.
DR   PomBase; SPAC8F11.08c; -.
DR   VEuPathDB; FungiDB:SPAC8F11.08c; -.
DR   eggNOG; KOG1516; Eukaryota.
DR   HOGENOM; CLU_744250_0_0_1; -.
DR   OMA; ISYLPNW; -.
DR   PRO; PR:Q9UT29; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013094; AB_hydrolase_3.
DR   Pfam; PF07859; Abhydrolase_3; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   4: Predicted;
KW   Endoplasmic reticulum; Hydrolase; Meiosis; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..376
FT                   /note="Uncharacterized protein C8F11.08c"
FT                   /id="PRO_0000362151"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   376 AA;  41754 MW;  AD69CF9E7BB1A883 CRC64;
     MGFATILYSI WVVLSSFVIL SAYQLEVRKF LVKLLSKIVI GASESNVASF FAFVSEKSLE
     AASVKFVATI IAERMGAQFS SFYDKIFFVD MLGLGSLFAL AAVNVLAARK LESELPASLE
     PSIGNRDQQK NSSLAKCFSR LFINDLHGTT VKRYPYISYL PNWLLAKNNA ERLVYKSHLL
     LNAYSPPKSA SASSVIVWVC GAKKSESIII PYLSSLGFFV VVPNYAQPPK FPLSDAVEFV
     SLCVDWIVEN AIYYDADPER IFFLGEDTGA SVALESLKHI RPNSVKGIFA LCPRSIQNLV
     WTNQSTIPMM TLHAGDVNPV SDSNDRESSE KASLIKNFVV PGAVPYYYEF TSPRTISTAT
     FIARWFFLVE DNKKTI